Display options
Share it on

Clin Cosmet Investig Dermatol. 2021 Sep 21;14:1311-1318. doi: 10.2147/CCID.S318748. eCollection 2021.

Tumor of the Nose - A Rare Manifestation of a Metastatic Lung Cancer.

Clinical, cosmetic and investigational dermatology

Aleksandra Bolewska, Monika Słowińska, Agata Błońska, Justyna Ceryn, Bartłomiej Grala, Joanna Narbutt, Magdalena Ciążyńska, Wojciech Małecki, Małgorzata Skibińska, Aleksandra Lesiak, Elwira Paluchowska, Witold Owczarek

Affiliations

  1. Department of Dermatology, Military Institute of Medicine, Warsaw, Poland.
  2. Department of Dermatology, Pediatric Dermatology and Oncology, Medical University of Lodz, ?ód?, Poland.
  3. Department of Pathology, Military Institute of Medicine, Warsaw, Poland.
  4. Department of Proliferative Diseases, Nicolaus Copernicus Multidisciplinary Centre for Oncology and Traumatology, ?ód?, Poland.
  5. Department of Clinical Oncology and Chemotherapy, Podd?bice Health Centre, Podd?bice, Poland.

PMID: 34584435 PMCID: PMC8464336 DOI: 10.2147/CCID.S318748

Abstract

Lung cancer most often metastasizes to the central nervous system, bone and liver. Although metastases to the skin are quite rare, it is estimated that they may be the first clinical manifestation of this disease in 0.7%-12% of cases. Metastases to the skin are caused by adenocarcinoma (about 30%), squamous cell carcinoma (30%) and undifferentiated carcinoma (40%). Nasal tip metastases are extremely rare. They can be confused with more common skin problems, including non-melanoma skin cancers, rhinophyma, inflammatory tumors or infectious diseases. We report two patients with a tumor on the nose, which proved to be the first sign of the metastatic lung cancer.

© 2021 Bolewska et al.

Keywords: lung cancer; skin metastasis; tumor; ulceration

Conflict of interest statement

The authors declare no conflicts of interest.

References

  1. BMJ Case Rep. 2014 Jan 31;2014: - PubMed
  2. Intern Med. 1996 Jun;35(6):459-62 - PubMed
  3. Postgrad Med. 1986 Dec;80(8):111-6 - PubMed
  4. J Cancer Res Clin Oncol. 2012 Oct;138(10):1613-7 - PubMed
  5. Ann Surg. 1940 Jul;112(1):138-49 - PubMed
  6. Ann Diagn Pathol. 2019 Dec;43:151399 - PubMed
  7. Chest. 1994 Nov;106(5):1448-50 - PubMed
  8. Cancer. 1972 May;29(5):1298-307 - PubMed
  9. Chin Med J (Engl). 2017 5th Jan 2017;130(1):115-116 - PubMed
  10. Dermatol Clin. 2019 Oct;37(4):545-554 - PubMed
  11. Chest. 1990 Mar;97(3):757-9 - PubMed
  12. Arch Dermatol. 1972 Jun;105(6):862-8 - PubMed
  13. Acta Derm Venereol. 2013 Sep 4;93(5):569-72 - PubMed
  14. J Dermatol Case Rep. 2017 Mar 31;11(1):9-11 - PubMed
  15. J Eur Acad Dermatol Venereol. 2011 Jun;25(6):722-6 - PubMed

Publication Types