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Front Neurosci. 2021 Aug 31;15:669535. doi: 10.3389/fnins.2021.669535. eCollection 2021.

Oscillatory Pattern of Sympathetic Nerve Bursts Is Associated With Baroreflex Function in Heart Failure Patients With Reduced Ejection Fraction.

Frontiers in neuroscience

Edgar Toschi-Dias, Nicola Montano, Eleonora Tobaldini, Patrícia F Trevizan, Raphaela V Groehs, Ligia M Antunes-Correa, Thais S Nobre, Denise M Lobo, Allan R K Sales, Linda M Ueno-Pardi, Luciana D N J de Matos, Patrícia A Oliveira, Ana Maria F W Braga, Maria Janieire N N Alves, Carlos E Negrão, Maria Urbana P B Rondon

Affiliations

  1. Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
  2. Department of Internal Medicine, Fondazione IRCSS Ca' Granda, Ospedale Maggiore Policlínico, Milan, Italy.
  3. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
  4. School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil.

PMID: 34531714 PMCID: PMC8439256 DOI: 10.3389/fnins.2021.669535

Abstract

Sympathetic hyperactivation and baroreflex dysfunction are hallmarks of heart failure with reduced ejection fraction (HFrEF). However, it is unknown whether the progressive loss of phasic activity of sympathetic nerve bursts is associated with baroreflex dysfunction in HFrEF patients. Therefore, we investigated the association between the oscillatory pattern of muscle sympathetic nerve activity (LF

Copyright © 2021 Toschi-Dias, Montano, Tobaldini, Trevizan, Groehs, Antunes-Correa, Nobre, Lobo, Sales, Ueno-Pardi, de Matos, Oliveira, Braga, Alves, Negrão and Rondon.

Keywords: baroreflex control; cardiovascular variabilities; heart failure; oscillatory pattern; sympathetic nervous system

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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