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Vojdani A. Elevated IgG Antibody to Aluminum Bound to Human Serum Albumin in Patients with Crohn's, Celiac and Alzheimer's Disease. Toxics. 2021;9(9)doi: 10.3390/toxics9090212.
Vojdani, A. (2021). Elevated IgG Antibody to Aluminum Bound to Human Serum Albumin in Patients with Crohn's, Celiac and Alzheimer's Disease. Toxics, 9(9), . https://doi.org/10.3390/toxics9090212
Vojdani, Aristo. "Elevated IgG Antibody to Aluminum Bound to Human Serum Albumin in Patients with Crohn's, Celiac and Alzheimer's Disease." Toxics vol. 9,9 (2021). doi: https://doi.org/10.3390/toxics9090212
Vojdani A. Elevated IgG Antibody to Aluminum Bound to Human Serum Albumin in Patients with Crohn's, Celiac and Alzheimer's Disease. Toxics. 2021 Sep 04;9(9). doi: 10.3390/toxics9090212. PMID: 34564363; PMCID: PMC8473134.
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Toxics. 2021 Sep 04;9(9). doi: 10.3390/toxics9090212.

Elevated IgG Antibody to Aluminum Bound to Human Serum Albumin in Patients with Crohn's, Celiac and Alzheimer's Disease.

Toxics

Aristo Vojdani

Affiliations

  1. Immunosciences Lab, Inc., 822 S. Robertson Blvd, Ste. 312, Los Angeles, CA 90035, USA.
  2. Cyrex Laboratories, LLC. 2602 South 24th St., Phoenix, AZ 85034, USA.

PMID: 34564363 PMCID: PMC8473134 DOI: 10.3390/toxics9090212

Abstract

Aluminum is in our water and food, and is used as an adjuvant in vaccines. About 40% of the ingested dose accumulates within the intestinal mucosa, making the gut the main target of inflammation and autoimmunity; about 1% accumulates in the skeletal system and brain, inducing the cross-linking of amyloid-β-42 peptide and the formation of amyloid aggregates associated with Alzheimer's disease. To examine whether the accumulation of aluminum in the gut and brain tissues results in neoantigen formation, we bound aluminum compounds to human serum albumin. We used ELISA to measure IgG antibody in 94 different sera from healthy controls and 47 sera from each group of patients: anti-

Keywords: Alzheimer’s; Crohn’s; adjuvant; aluminum; autoimmunity; celiac; neoantigen

References

  1. Mod Pathol. 1989 May;2(3):222-6 - PubMed
  2. J Pediatr Neurosci. 2013 Jan;8(1):81-2 - PubMed
  3. Neurotoxicology. 2007 Nov;28(6):1068-78 - PubMed
  4. Front Neurol. 2015 Feb 05;6:4 - PubMed
  5. J Appl Toxicol. 2015 Apr;35(4):383-97 - PubMed
  6. Hum Pathol. 1987 Jan;18(1):50-4 - PubMed
  7. Biol Trace Elem Res. 2000 Jul;76(1):31-55 - PubMed
  8. Lupus. 2012 Feb;21(2):223-30 - PubMed
  9. Mucosal Immunol. 2014 May;7(3):589-601 - PubMed
  10. Front Neurol. 2014 Sep 05;5:167 - PubMed
  11. Biochem J. 1991 Dec 1;280 ( Pt 2):527-32 - PubMed
  12. Neurosci Lett. 1990 Mar 2;110(1-2):221-6 - PubMed
  13. Vaccine. 2013 Sep 13;31(40):4362-7 - PubMed
  14. J Alzheimers Dis. 2018;63(2):847-860 - PubMed
  15. Arch Toxicol. 2019 Dec;93(12):3503-3521 - PubMed
  16. BMC Pediatr. 2010 Aug 31;10:63 - PubMed
  17. Med Hypotheses. 1999 Jul;53(1):22-3 - PubMed
  18. PLoS One. 2014 May 30;9(5):e98409 - PubMed
  19. Gut. 1994 Aug;35(8):1053-7 - PubMed
  20. Pharm Biotechnol. 1995;6:229-48 - PubMed
  21. J Alzheimers Dis. 2016 Oct 18;54(4):1333-1338 - PubMed
  22. J Med Case Rep. 2014 Feb 10;8:41 - PubMed
  23. Vaccine. 2005 Feb 18;23(13):1588-95 - PubMed
  24. Crit Rev Clin Lab Sci. 1997;34(5):439-74 - PubMed
  25. Int J Alzheimers Dis. 2011 Mar 08;2011:276393 - PubMed
  26. J Immunol. 2009 Oct 1;183(7):4403-14 - PubMed
  27. Nat Rev Immunol. 2009 Apr;9(4):287-93 - PubMed
  28. J Inorg Biochem. 2015 Nov;152:214-8 - PubMed
  29. J Alzheimers Dis Rep. 2021 Apr 09;5(1):283-294 - PubMed
  30. Gut. 1996 Mar;38(3):390-5 - PubMed
  31. J Alzheimers Dis. 2020;73(4):1627-1635 - PubMed
  32. J Alzheimers Dis. 2018;65(4):1267-1281 - PubMed
  33. World Allergy Organ J. 2015 Feb 28;8(1):7 - PubMed
  34. J Trace Elem Med Biol. 2018 Mar;46:76-82 - PubMed

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