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Wang ZZ, Zhou XB, Wang Y, et al. Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery. World J Gastroenterol. 2021;27(35):5958-5966doi: 10.3748/wjg.v27.i35.5958.
Wang, Z. Z., Zhou, X. B., Wang, Y., Mao, X. L., Ye, L. P., Yan, L. L., Chen, Y. H., Song, Y. Q., Cai, Y., Xu, S. W., & Li, S. W. (2021). Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery. World journal of gastroenterology, 27(35), 5958-5966. https://doi.org/10.3748/wjg.v27.i35.5958
Wang, Zhen-Zhen, et al. "Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery." World journal of gastroenterology vol. 27,35 (2021): 5958-5966. doi: https://doi.org/10.3748/wjg.v27.i35.5958
Wang ZZ, Zhou XB, Wang Y, Mao XL, Ye LP, Yan LL, Chen YH, Song YQ, Cai Y, Xu SW, Li SW. Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery. World J Gastroenterol. 2021 Sep 21;27(35):5958-5966. doi: 10.3748/wjg.v27.i35.5958. PMID: 34629812; PMCID: PMC8475004.
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World J Gastroenterol. 2021 Sep 21;27(35):5958-5966. doi: 10.3748/wjg.v27.i35.5958.

Effectiveness and safety of over-the-scope clip in closing perforations after duodenal surgery.

World journal of gastroenterology

Zhen-Zhen Wang, Xian-Bin Zhou, Yi Wang, Xin-Li Mao, Li-Ping Ye, Ling-Ling Yan, Ya-Hong Chen, Ya-Qi Song, Yue Cai, Shi-Wen Xu, Shao-Wei Li

Affiliations

  1. Key Laboratory of Minimally Invasive Techniques and Rapid Rehabilitation of Digestive System Tumor of Zhejiang Province, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China.
  2. Health Management Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai 317000, Zhejiang Province, China.
  3. Taizhou Hospital of Zhejiang Province, Wenzhou Medical University, Linhai 317000, Zhejiang Province, China.

PMID: 34629812 PMCID: PMC8475004 DOI: 10.3748/wjg.v27.i35.5958

Abstract

BACKGROUND: Endoscopic resection of duodenal subepithelial lesions (SELs) is a difficult procedure with a high risk of perforation. At present, dealing with perforation after endoscopic resection of duodenal SELs is still considered a great challenge.

AIM: To evaluate the effectiveness and safety of an over-the-scope clip (OTSC) in the treatment of perforation post-endoscopic resection of duodenal SELs.

METHODS: From May 2015 to November 2019, 18 patients with perforation following endoscopic resection of duodenal SELs were treated with OTSCs. Data comprising the rate of complete resection, closure of intraprocedural perforation, delayed bleeding, delayed perforation, and postoperative infection were extracted.

RESULTS: The rate of complete removal of duodenal SELs and successful closure of the perforation was 100%. The median perforation size was 1 cm in diameter. Seventeen patients had minor intraoperative bleeding, while the remaining 1 patient had considerable amount of bleeding during the procedure. Seven patients had postoperative abdominal infections, of which 1 patient developed an abscess in the right iliac fossa and another patient developed septic shock. All 18 patients recovered and were discharged. No delayed bleeding or perforation was reported. The mean time taken to resume normal diet after the procedure was 6.5 d. The mean postoperative hospital stay was 9.5 d. No residual or recurrent lesions were detected during the follow-up period (15-66 mo).

CONCLUSION: Closing a perforation after endoscopic resection of duodenal SELs with OTSCs seems to be an effective and reasonably safe therapeutic method.

©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

Keywords: Duodenal subepithelial lesion; Effectiveness; Endoscopic resection; Over-the-scope clip; Perforation; Safety

Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflict interests.

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