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Spiroux de Vendômois J, Bourdineaud JP, Apoteker A, et al. Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security. Toxicol Res. 2021;37(4):405-419doi: 10.1007/s43188-020-00075-w.
Spiroux de Vendômois, J., Bourdineaud, J. P., Apoteker, A., Defarge, N., Gaillard, E., Lepage, C., Testart, J., & Vélot, C. (2021). Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security. Toxicological research, 37(4), 405-419. https://doi.org/10.1007/s43188-020-00075-w
Spiroux de Vendômois, Joël, et al. "Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security." Toxicological research vol. 37,4 (2021): 405-419. doi: https://doi.org/10.1007/s43188-020-00075-w
Spiroux de Vendômois J, Bourdineaud JP, Apoteker A, Defarge N, Gaillard E, Lepage C, Testart J, Vélot C. Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security. Toxicol Res. 2021 Jan 25;37(4):405-419. doi: 10.1007/s43188-020-00075-w. eCollection 2021 Oct. PMID: 34631497; PMCID: PMC8476664.
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Toxicol Res. 2021 Jan 25;37(4):405-419. doi: 10.1007/s43188-020-00075-w. eCollection 2021 Oct.

Trans-disciplinary diagnosis for an in-depth reform of regulatory expertise in the field of environmental toxicology and security.

Toxicological research

Joël Spiroux de Vendômois, Jean-Paul Bourdineaud, Arnaud Apoteker, Nicolas Defarge, Emilie Gaillard, Corinne Lepage, Jacques Testart, Christian Vélot

Affiliations

  1. Committee for Independent Research and Information on Genetic Engineering (CRIIGEN), 42 rue de Lisbonne, 75008 Paris, France.
  2. CNRS, UMR 5234, Laboratory of Fundamental Microbiology and Pathogenicity, European Institute of Chemistry and Biology, University of Bordeaux, Bordeaux, France.
  3. Institute of Integrative Biology IBZ, Swiss Federal Institute of Technology, Universitätstrasse 16, 8092 Zurich, Switzerland.
  4. Université de Caen-Basse Normandie, Esplanade de la Paix, 14000 Caen, France.
  5. Sciences Citoyennes, 38 rue Saint Sabin, 75011 Paris, France.
  6. Laboratory VEAC, University Paris-Saclay, Faculty of Sciences, Bât. 350-RdC, Avenue Jean Perrin, 91405 Orsay, France.
  7. Risk Pole MRSH-CNRS, EA2608, University of Caen, Esplanade de la Paix, 14032 Caen, France.

PMID: 34631497 PMCID: PMC8476664 DOI: 10.1007/s43188-020-00075-w

Abstract

Repeated health and environmental scandals, the loss of biodiversity and the recent burst of chronic diseases constantly remind us the inability of public authorities and risk assessment agencies to protect health and the environment. After reviewing the main shortcomings of our evaluation system of chemicals and new technologies, supported by some concrete examples, we develop a number of proposals to reform both the risk assessment agencies and the evaluation processes. We especially propose the establishment of an independent structure, a High Authority of Expertise, supervising, either at European level or at national level, all the evaluation agencies, and ensuring the transparency, the methodology and the deontology of the expertise. In addition to modifying the evaluation protocols, both in their nature and in their content, especially in order to adapt them to current pollutants such as endocrine disruptors, we propose a reform of the expertise processes based on transparency, contradiction, and greater democracy, including close collaboration between the institutional and scientific parties on the one hand and the whole civil society on the other. All the proposals we make are inspired by the desire to prevent, through appropriate mechanisms, the human, health, ecological, but also economic consequences of contemporary technological choices.

© Korean Society of Toxicology 2021.

Keywords: Conflict of interest; Deontology; Endocrine disrupter; High Authority of Expertise; Pesticide; Regulatory evaluation

Conflict of interest statement

Conflict of interestThe authors have no conflict of interest to disclose. The views expressed in this article are those of the authors and of CRIIGEN, and do not necessarily reflect the views or polic

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