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Genes (Basel). 2021 Sep 13;12(9). doi: 10.3390/genes12091407.

Common and Unique Genetic Background between Attention-Deficit/Hyperactivity Disorder and Excessive Body Weight.

Genes

Monika Dmitrzak-Weglarz, Elzbieta Paszynska, Karolina Bilska, Paula Szczesniewska, Ewa Bryl, Joanna Duda, Agata Dutkiewicz, Marta Tyszkiewicz-Nwafor, Piotr Czerski, Tomasz Hanc, Agnieszka Slopien

Affiliations

  1. Department of Psychiatric Genetics, Poznan University of Medical Sciences, 60-806 Poznan, Poland.
  2. Department of Integrated Dentistry, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
  3. Institute of Human Biology and Evolution, Faculty of Biology, Adam Mickiewicz University, 61-614 Poznan, Poland.
  4. Department of Child and Adolescent Psychiatry, Poznan University of Medical Sciences, 60-572 Poznan, Poland.

PMID: 34573389 PMCID: PMC8464917 DOI: 10.3390/genes12091407

Abstract

Comorbidity studies show that children with ADHD have a higher risk of being overweight and obese than healthy children. This study aimed to assess the genetic alternations that differ between and are shared by ADHD and excessive body weight (EBW). The sample consisted of 743 Polish children aged between 6 and 17 years. We analyzed a unique set of genes and polymorphisms selected for ADHD and/or obesity based on gene prioritization tools. Polymorphisms in the

Keywords: attention-deficit/hyperactivity disorder; case-control association study; excessive body weight; whole exome sequencing

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