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Grover M, Berumen A, Peters S, et al. Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply. Aliment Pharmacol Ther. 2021;54(9):1215-1216doi: 10.1111/apt.16613.
Grover, M., Berumen, A., Peters, S., Wei, T., Breen-Lyles, M., Harmsen, W. S., Busciglio, I., Burton, D., Vazquez Roque, M., DeVault, K. R., Camilleri, M., Wallace, M., Dasari, S., Neumann, H., & Houghton, L. A. (2021). Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply. Alimentary pharmacology & therapeutics, 54(9), 1215-1216. https://doi.org/10.1111/apt.16613
Grover, Madhusudan, et al. "Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply." Alimentary pharmacology & therapeutics vol. 54,9 (2021): 1215-1216. doi: https://doi.org/10.1111/apt.16613
Grover M, Berumen A, Peters S, Wei T, Breen-Lyles M, Harmsen WS, Busciglio I, Burton D, Vazquez Roque M, DeVault KR, Camilleri M, Wallace M, Dasari S, Neumann H, Houghton LA. Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply. Aliment Pharmacol Ther. 2021 Nov;54(9):1215-1216. doi: 10.1111/apt.16613. PMID: 34637534.
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Aliment Pharmacol Ther. 2021 Nov;54(9):1215-1216. doi: 10.1111/apt.16613.

Editorial: understanding IBS pathophysiology through "converging channels" of research-authors' reply.

Alimentary pharmacology & therapeutics

Madhusudan Grover, Antonio Berumen, Stephanie Peters, Ting Wei, Margaret Breen-Lyles, William S Harmsen, Irene Busciglio, Duane Burton, Maria Vazquez Roque, Kenneth R DeVault, Michael Camilleri, Michael Wallace, Surendra Dasari, Helmut Neumann, Lesley A Houghton

Affiliations

  1. Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  2. Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  3. Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
  4. Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, FL, USA.
  5. Department of Medicine I, University Medical Center, Mainz, Germany.
  6. GastroZentrum Lippe, Bad Salzuflen, Germany.
  7. Leeds Institute of Medical Research at St James's, University of Leeds, Leeds, UK.

PMID: 34637534 DOI: 10.1111/apt.16613

[No abstract available.]

References

  1. Grover M, Berumen A, Peters S, et al. Intestinal chemosensitivity in irritable bowel syndrome associates with small intestinal TRPV channel expression. Aliment Pharmacol Ther. 2021;54:1179-1192. - PubMed
  2. Elwing JE, Sayuk GS. Editorial: understanding IBS pathophysiology through "converging channels" of research. Aliment Pharmacol Ther. 2021;54:1213-1214. - PubMed
  3. Ford AC, Sperber AD, Corsetti M, Camilleri M. Irritable bowel syndrome. Lancet. 2020;396:1675-1688. - PubMed
  4. Akbar A, Yiangou Y, Facer P, Walters JRF, Anand P, Ghosh S. Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut. 2008;57:923-929. - PubMed
  5. Balemans D, Aguilera-Lizarraga J, Florens MV, et al. Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2019;316:G338-G349. - PubMed
  6. Wouters MM, Balemans D, Van Wanrooy S, et al. Histamine receptor H1-mediated sensitization of TRPV1 mediates visceral hypersensitivity and symptoms in patients with irritable bowel syndrome. Gastroenterology. 2016;150(4):875-887.e9. https://doi.org/10.1053/j.gastro.2015.12.034 - PubMed
  7. Brizuela M, Castro J, Harrington AM, Brierley SM. Pruritogenic mechanisms and gut sensation: putting the "irritant" into irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 2021;320:G1131-G1141. - PubMed
  8. Seebohm G, Schreiber JA. Beyond hot and spicy: TRPV channels and their pharmacological modulation. Cell Physiol Biochem. 2021;55:108-130. - PubMed

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