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Kadry Z, Schaefer E, Krok K, et al. Excellent outcomes with liver transplantation in hepatopulmonary syndrome across pre-transplant PaO. JHEP Rep. 2021;3(5):100351doi: 10.1016/j.jhepr.2021.100351.
Kadry, Z., Schaefer, E., Krok, K., Faust, A., Stine, J. G., Schreibman, I. R., Bezinover, D., & Riley, T. R. (2021). Excellent outcomes with liver transplantation in hepatopulmonary syndrome across pre-transplant PaO. JHEP reports : innovation in hepatology, 3(5), 100351. https://doi.org/10.1016/j.jhepr.2021.100351
Kadry, Zakiyah, et al. "Excellent outcomes with liver transplantation in hepatopulmonary syndrome across pre-transplant PaO." JHEP reports : innovation in hepatology vol. 3,5 (2021): 100351. doi: https://doi.org/10.1016/j.jhepr.2021.100351
Kadry Z, Schaefer E, Krok K, Faust A, Stine JG, Schreibman IR, Bezinover D, Riley TR. Excellent outcomes with liver transplantation in hepatopulmonary syndrome across pre-transplant PaO. JHEP Rep. 2021 Aug 12;3(5):100351. doi: 10.1016/j.jhepr.2021.100351. eCollection 2021 Oct. PMID: 34604726; PMCID: PMC8473556.
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JHEP Rep. 2021 Aug 12;3(5):100351. doi: 10.1016/j.jhepr.2021.100351. eCollection 2021 Oct.

Excellent outcomes with liver transplantation in hepatopulmonary syndrome across pre-transplant PaO.

JHEP reports : innovation in hepatology

Zakiyah Kadry, Eric Schaefer, Karen Krok, Alison Faust, Jonathan Gibson Stine, Ian Roy Schreibman, Dmitri Bezinover, Thomas Roberts Riley

Affiliations

  1. Division of Transplantation, Department of Surgery, Penn State College of Medicine, Hershey, PA, USA.
  2. Department of Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
  3. Division of Gastroenterology and Hepatology, Department of Medicine, Penn State College of Medicine, Hershey, PA, USA.
  4. Department of Anesthesiology, Penn State College of Medicine, Hershey, PA, USA.

PMID: 34604726 PMCID: PMC8473556 DOI: 10.1016/j.jhepr.2021.100351

Abstract

BACKGROUND & AIMS: Significantly worse survival has been reported in patients with hepatopulmonary syndrome (HPS) and partial pressure of arterial oxygen (PaO

METHODS: A retrospective analysis of 1,152 HPS candidates listed with an approved HPS model for end-stage liver disease (MELD) exception was performed. A Fine and Gray competing risks model was utilised to evaluate pre-transplant outcomes for PaO

RESULTS: Patients with a PaO

CONCLUSIONS: Patients with a PaO

LAY SUMMARY: A total of 1,152 patients with hepatopulmonary syndrome listed for liver transplant were analysed. Patients with a low PaO

© 2021 The Authors.

Keywords: CIF, cumulative incidence function; ECMO, extracorporeal membrane oxygenation; HPS, hepatopulmonary syndrome; HR, hazard ratio; Hepatopulmonary syndrome; Hypoxia; Liver transplantation; MELD, model for end-stage liver disease; NASH, non-alcoholic steatohepatitis; OPTN, Organ Procurement and Transplant Network; POPH, portopulmonary hypertension; PaO2, partial pressure of arterial oxygen; STAR, Standard Transplant Analysis and Research; UNOS, United Network for Organ Sharing

Conflict of interest statement

The authors have no conflicts of interest or financial disclosures to make. Please refer to the accompanying ICMJE disclosure forms for further details.

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