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Januszek RA, Bryniarski L, Siudak Z, et al. Predictors and trends of contrast use and radiation exposure in a large cohort of patients treated with percutaneous coronary interventions: Chronic total occlusion analysis based on a national registry. Cardiol J. 2021;doi: 10.5603/CJ.a2021.0124.
Januszek, R. A., Bryniarski, L., Siudak, Z., Malinowski, K. P., Surowiec, S., Bryniarski, K., Jędrychowska, M., Wańha, W., Bartuś, K., Wojakowski, W., Wójcik, J., Legutko, J., Surdacki, A., & Bartuś, S. (2021). Predictors and trends of contrast use and radiation exposure in a large cohort of patients treated with percutaneous coronary interventions: Chronic total occlusion analysis based on a national registry. Cardiology journal, . https://doi.org/10.5603/CJ.a2021.0124
Januszek, Rafał A, et al. "Predictors and trends of contrast use and radiation exposure in a large cohort of patients treated with percutaneous coronary interventions: Chronic total occlusion analysis based on a national registry." Cardiology journal vol. (2021). doi: https://doi.org/10.5603/CJ.a2021.0124
Januszek RA, Bryniarski L, Siudak Z, Malinowski KP, Surowiec S, Bryniarski K, Jędrychowska M, Wańha W, Bartuś K, Wojakowski W, Wójcik J, Legutko J, Surdacki A, Bartuś S. Predictors and trends of contrast use and radiation exposure in a large cohort of patients treated with percutaneous coronary interventions: Chronic total occlusion analysis based on a national registry. Cardiol J. 2021 Oct 13; doi: 10.5603/CJ.a2021.0124. Epub 2021 Oct 13. PMID: 34642921.
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Cardiol J. 2021 Oct 13; doi: 10.5603/CJ.a2021.0124. Epub 2021 Oct 13.

Predictors and trends of contrast use and radiation exposure in a large cohort of patients treated with percutaneous coronary interventions: Chronic total occlusion analysis based on a national registry.

Cardiology journal

Rafał A Januszek, Leszek Bryniarski, Zbigniew Siudak, Krzysztof Piotr Malinowski, Sławomir Surowiec, Krzysztof Bryniarski, Magdalena Jędrychowska, Wojciech Wańha, Krzysztof Bartuś, Wojciech Wojakowski, Jarosław Wójcik, Jacek Legutko, Andrzej Surdacki, Stanisław Bartuś

Affiliations

  1. Department of Cardiology and Cardiovascular Interventions, University Hospital, Krakow, Poland. [email protected].
  2. Department of Clinical Rehabilitation, University of Physical Education, Krakow, Poland. [email protected].
  3. Department of Cardiology and Cardiovascular Interventions, University Hospital, Krakow, Poland.
  4. Department of Cardiology, Jagiellonian University Medical College, Krakow, Poland.
  5. Collegium Medicum, Jan Kochanowski University, Kielce, Poland.
  6. Department of Interventional Cardiology, Institute of Cardiology, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
  7. Department of Cardiology and Structural Heart Diseases, Medical University of Silesia, Katowice, Poland.
  8. Department of Cardiovascular Surgery and Transplantology, Jagiellonian University Medical College, John Paul II Hospital, Krakow, Poland.
  9. Department of Cardiology, Hospital of Invasive Cardiology IKARDIA, Na??czów, Poland.

PMID: 34642921 DOI: 10.5603/CJ.a2021.0124

Abstract

BACKGROUND: The aim herein, was to assess predictors and current trends of radiation exposure and total contrast amount use in patients treated with percutaneous coronary intervention within chronic total occlusion (CTO PCI) and non-CTO PCI.

METHODS: Based on a nationwide registry (ORPKI), 535,857 patients treated with PCI between 2014 and 2018 were analysed. The study included 12,572 (2.34%) patients treated with CTO PCI. The CTO PCI and non-CTO PCI groups were compared before and after propensity score matching (PSM). Multifactorial mixed regression models were used to assess predictors of contrast amount use and radiation exposure.

RESULTS: The mean total contrast dose and radiation exposure decrease reached statistical significance in following years for the CTO PCI (p = 0.002 and p < 0.001) and non-CTO PCI groups (p < 0.001 and p < 0.001). Multifactorial analysis revealed that non-CTO PCI was a strong independent predictor of lower total contrast dose (estimate: -17.41; 95% confidence interval [CI]: -18.45 to -16.49, p < 0.001) and radiation exposure (estimate: -264.28; 95% CI: -273.75 to -254.81, p < 0.001). After PSM, it was confirmed that CTO PCI was an independent predictor of greater radiation exposure (estimate: 328.6; 95% CI: 289.1-368.1; p < 0.001) and total contrast dose (estimate: 30.5; 95% CI: 27.28-33.74; p < 0.001).

CONCLUSIONS: Contrast dose and radiation exposure have decreased in previous years with regard to the CTO PCI and non-CTO PCI groups. CTO PCI was found to be an independent predictor of greater total contrast dose and radiation exposure in the overall group of patients treated with PCI.

Keywords: chronic total occlusion; contrast dose; percutaneous coronary intervention; radiation exposure

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