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Masoomian B, Eshraghi B, Latifi G, et al. Efficacy of probing adjunctive with low-dose mitomycin-C irrigation for the treatment of epiphora in adults with nasolacrimal duct stenosis. Taiwan J Ophthalmol. 2020;11(3):287-291doi: 10.4103/tjo.tjo_25_20.
Masoomian, B., Eshraghi, B., Latifi, G., & Esfandiari, H. (2021). Efficacy of probing adjunctive with low-dose mitomycin-C irrigation for the treatment of epiphora in adults with nasolacrimal duct stenosis. Taiwan journal of ophthalmology, 11(3), 287-291. https://doi.org/10.4103/tjo.tjo_25_20
Masoomian, Babak, et al. "Efficacy of probing adjunctive with low-dose mitomycin-C irrigation for the treatment of epiphora in adults with nasolacrimal duct stenosis." Taiwan journal of ophthalmology vol. 11,3 (2021): 287-291. doi: https://doi.org/10.4103/tjo.tjo_25_20
Masoomian B, Eshraghi B, Latifi G, Esfandiari H. Efficacy of probing adjunctive with low-dose mitomycin-C irrigation for the treatment of epiphora in adults with nasolacrimal duct stenosis. Taiwan J Ophthalmol. 2020 Oct 19;11(3):287-291. doi: 10.4103/tjo.tjo_25_20. eCollection 2021. PMID: 34703745; PMCID: PMC8493988.
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Taiwan J Ophthalmol. 2020 Oct 19;11(3):287-291. doi: 10.4103/tjo.tjo_25_20. eCollection 2021.

Efficacy of probing adjunctive with low-dose mitomycin-C irrigation for the treatment of epiphora in adults with nasolacrimal duct stenosis.

Taiwan journal of ophthalmology

Babak Masoomian, Bahram Eshraghi, Golshan Latifi, Hossein Esfandiari

Affiliations

  1. Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

PMID: 34703745 PMCID: PMC8493988 DOI: 10.4103/tjo.tjo_25_20

Abstract

PURPOSE: The purpose of the study was to investigate the efficacy of adjunctive low-dose mitomycin-C (MMC) during successful lacrimal duct probing in adults with nasolacrimal ducts (NLDs) stenosis.

MATERIALS AND METHODS: This is a prospective case-control study on patients with NLD stenosis who were randomized into two groups. All patients underwent probing without or with an application of MMC. Former group received 0.2 mg/ml MMC irrigation for 5 min. The main outcome measures were objective evaluation of patency with irrigation, as well as patients' subjective assessment of improvement.

RESULTS: There were 73 eyes in 58 consecutive patients; patient mean age ranged from 19 to 78 years (mean 44 years). Female included larger group of patients (63%) and mean duration of the symptoms was 26.1 months (range, 2-120 months). After mean follow-up of 11 months (range, 9-14 months), 23 (60%) of the 38 eyes in the MMC groups and 8 (22%) of the 35 eyes in control group had complete response and remained symptom free. This difference was statistically significant (

CONCLUSION: This study suggests acceptable long-term results for probing adjunctive with MMC irrigation for adults with NLD stenosis that can be recommended as a simple and effective procedure for these patients.

Copyright: © 2020 Taiwan J Ophthalmol.

Keywords: Adults; epiphora; mitomycin-C; nasolacrimal duct stenosis; probing

Conflict of interest statement

The authors declare that there are no conflicts of interests of this paper.

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