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Mouton JP, Jobanputra N, Tatz G, et al. Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review. Pharmacol Res Perspect. 2021;9(6):e00875doi: 10.1002/prp2.875.
Mouton, J. P., Jobanputra, N., Tatz, G., & Cohen, K. (2021). Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review. Pharmacology research & perspectives, 9(6), e00875. https://doi.org/10.1002/prp2.875
Mouton, Johannes P, et al. "Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review." Pharmacology research & perspectives vol. 9,6 (2021): e00875. doi: https://doi.org/10.1002/prp2.875
Mouton JP, Jobanputra N, Tatz G, Cohen K. Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review. Pharmacol Res Perspect. 2021 Dec;9(6):e00875. doi: 10.1002/prp2.875. PMID: 34738728; PMCID: PMC8569857.
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Pharmacol Res Perspect. 2021 Dec;9(6):e00875. doi: 10.1002/prp2.875.

Serious adverse drug reactions in sub-Saharan Africa in the era of antiretroviral treatment: A systematic review.

Pharmacology research & perspectives

Johannes P Mouton, Nicole Jobanputra, Gayle Tatz, Karen Cohen

Affiliations

  1. Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Cape Town, South Africa.

PMID: 34738728 PMCID: PMC8569857 DOI: 10.1002/prp2.875

Abstract

We aimed to summarize and describe the burden of serious adverse drug reactions (ADRs) in sub-Saharan Africa (SSA) in the era of antiretroviral therapy. We searched Medline, CINAHL, Africa-Wide Information, Scopus, and Web of Science, without language restriction up to March 2021. We hand-searched reference lists, conference abstracts, and dissertation databases. We included studies reporting proportions of admissions attributed to ADRs, admissions prolonged by ADRs, or in-hospital deaths attributed to ADRs. Two reviewers independently screened the studies, reviewed the study quality using a previously published tool, and extracted the data. We tested for heterogeneity using I

© 2021 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics.

Keywords: drug safety; medicine safety; pharmacoepidemiology; systematic review

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