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Gaál Z, Jakab Z, Kárai B, et al. Recent Advances in the Management of Pediatric Acute Myeloid Leukemia-Report of the Hungarian Pediatric Oncology-Hematology Group. Cancers (Basel). 2021;13(20)doi: 10.3390/cancers13205078.
Gaál, Z., Jakab, Z., Kárai, B., Ujfalusi, A., Petrás, M., Kállay, K., Kelemen, �. �., Simon, R., Kriván, G., Kovács, G. T., Kiss, C., & Szegedi, I. (2021). Recent Advances in the Management of Pediatric Acute Myeloid Leukemia-Report of the Hungarian Pediatric Oncology-Hematology Group. Cancers, 13(20), . https://doi.org/10.3390/cancers13205078
Gaál, Zsuzsanna, et al. "Recent Advances in the Management of Pediatric Acute Myeloid Leukemia-Report of the Hungarian Pediatric Oncology-Hematology Group." Cancers vol. 13,20 (2021). doi: https://doi.org/10.3390/cancers13205078
Gaál Z, Jakab Z, Kárai B, Ujfalusi A, Petrás M, Kállay K, Kelemen Á, Simon R, Kriván G, Kovács GT, Kiss C, Szegedi I. Recent Advances in the Management of Pediatric Acute Myeloid Leukemia-Report of the Hungarian Pediatric Oncology-Hematology Group. Cancers (Basel). 2021 Oct 11;13(20). doi: 10.3390/cancers13205078. PMID: 34680225; PMCID: PMC8534106.
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Cancers (Basel). 2021 Oct 11;13(20). doi: 10.3390/cancers13205078.

Recent Advances in the Management of Pediatric Acute Myeloid Leukemia-Report of the Hungarian Pediatric Oncology-Hematology Group.

Cancers

Zsuzsanna Gaál, Zsuzsanna Jakab, Bettina Kárai, Anikó Ujfalusi, Miklós Petrás, Krisztián Kállay, Ágnes Kelemen, Réka Simon, Gergely Kriván, Gábor T Kovács, Csongor Kiss, István Szegedi

Affiliations

  1. Department of Pediatric Hematology-Oncology, Institute of Pediatrics, University of Debrecen, 4032 Debrecen, Hungary.
  2. National Childhood Cancer Registry, 1094 Budapest, Hungary.
  3. Department of Laboratory Medicine, University of Debrecen, 4032 Debrecen, Hungary.
  4. Division of Pediatric Hematology/Oncology, Velkey László Child's Health Center, 3526 Miskolc, Hungary.
  5. Pediatric Hematology and Stem Cell Transplantation Department, Central Hospital of Southern Pest, National Institute of Hematology and Infectious Diseases, 1097 Budapest, Hungary.
  6. Second Department of Pediatrics, Semmelweis University, 1094 Budapest, Hungary.

PMID: 34680225 PMCID: PMC8534106 DOI: 10.3390/cancers13205078

Abstract

Outcome measures of pediatric acute myeloid leukemia (AML) improved considerably between 1990 and 2011 in Hungary. Since 2012, efforts of the Hungarian Pediatric Oncology-Hematology Group (HPOG) included the reduction in the number of treatment centers, contemporary diagnostic procedures, vigorous supportation, enhanced access to hematopoietic stem cell transplantation (HSCT), and to targeted therapies. The major aim of our study was to evaluate AML treatment results of HPOG between 2012 and 2019 with 92 new patients registered (52 males, 40 females, mean age 7.28 years). Two periods were distinguished: 2012-2015 and 2016-2019 (55 and 37 patients, respectively). During these periods, 2 y OS increased from 63.6% to 71.4% (

Keywords: Hungarian Pediatric Oncology-Hematology Group; acute myeloid leukemia; acute promyelocytic leukemia; multidimensional flow cytometry; survival outcomes

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