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Campese VD, Brannigan LA, LeDoux JE. Conditional Control of Instrumental Avoidance by Context Following Extinction. Front Behav Neurosci. 2021;15:730113doi: 10.3389/fnbeh.2021.730113.
Campese, V. D., Brannigan, L. A., & LeDoux, J. E. (2021). Conditional Control of Instrumental Avoidance by Context Following Extinction. Frontiers in behavioral neuroscience, 15730113. https://doi.org/10.3389/fnbeh.2021.730113
Campese, Vincent D, et al. "Conditional Control of Instrumental Avoidance by Context Following Extinction." Frontiers in behavioral neuroscience vol. 15 (2021): 730113. doi: https://doi.org/10.3389/fnbeh.2021.730113
Campese VD, Brannigan LA, LeDoux JE. Conditional Control of Instrumental Avoidance by Context Following Extinction. Front Behav Neurosci. 2021 Sep 28;15:730113. doi: 10.3389/fnbeh.2021.730113. eCollection 2021. PMID: 34650411; PMCID: PMC8505733.
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Front Behav Neurosci. 2021 Sep 28;15:730113. doi: 10.3389/fnbeh.2021.730113. eCollection 2021.

Conditional Control of Instrumental Avoidance by Context Following Extinction.

Frontiers in behavioral neuroscience

Vincent D Campese, Lauren A Brannigan, Joseph E LeDoux

Affiliations

  1. Department of Psychology, University of Evansville, Evansville, IN, United States.
  2. Center for Neural Science, New York University, New York, NY, United States.
  3. Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, United States.

PMID: 34650411 PMCID: PMC8505733 DOI: 10.3389/fnbeh.2021.730113

Abstract

Using rodents, three training arrangements (i.e., ABB vs. ABA, AAA vs. AAB and ABB vs. ABC) explored whether extinction influences the expression of avoidance in a manner controlled by context. Retention testing following extinction showed that more avoidance responding (i.e., renewal) was observed when extinguished cues were tested outside of the context where they had undergone extinction. In contrast, response rates were significantly lower when stimuli were tested within the context where extinction learning had occurred. These findings add to the emerging literature assessing the role of Pavlovian extinction processes in the development of instrumental avoidance responding by demonstrating conditional control over extinguished responding by context. This study was conducted using a within-subjects approach that minimized the potential for context-outcome associations to bias responding, and thus, reflects hierarchical control over behavior based on the specific associative status of each tested cue in each training context.

Copyright © 2021 Campese, Brannigan and LeDoux.

Keywords: avoidance; context; extinction; instrumental; renewal

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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