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Antibiotics (Basel). 2021 Oct 16;10(10). doi: 10.3390/antibiotics10101260.

Efficacy of the Endolysin-Based Antibacterial Gel for Treatment of Anaerobic Infection Caused by .

Antibiotics (Basel, Switzerland)

Daria V Vasina, Nataliia P Antonova, Aleksei M Vorobev, Aleksei I Laishevtsev, Andrei V Kapustin, Eldar R Zulkarneev, Svetlana S Bochkareva, Irina A Kiseleva, Mariia N Anurova, Andrei V Aleshkin, Artem P Tkachuk, Vladimir A Gushchin

Affiliations

  1. N.F. Gamaleya National Research Centre for Epidemiology and Microbiology, Ministry of Health of the Russian Federation, 123098 Moscow, Russia.
  2. G.N. Gabrichevsky Moscow Research Institute for Epidemiology and Microbiology, 125212 Moscow, Russia.
  3. Federal State Budget Scientific Institution "Federal Scientific Centre VIEV" (FSC VIEV), 117218 Moscow, Russia.
  4. Department of Pharmaceutical Technology, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119435 Moscow, Russia.
  5. Department of Virology, Biological Faculty, Lomonosov Moscow State University, 119991 Moscow, Russia.

PMID: 34680839 PMCID: PMC8532708 DOI: 10.3390/antibiotics10101260

Abstract

Abscess formation is a common complication of severe life-threatening infections caused by obligate anaerobes.

Keywords: Fusobacterium necrophorum; anaerobes; animal model; endolysin; enzybiotics; gel formulation; topical treatment

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