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Auguste A, Gathere S, Pinheiro PS, et al. Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3. Cancer Epidemiol. 2021;75:102053doi: 10.1016/j.canep.2021.102053.
Auguste, A., Gathere, S., Pinheiro, P. S., Adebamowo, C., Akintola, A., Alleyne-Mike, K., Anderson, S. G., Ashing, K., Awittor, F. K., Awuah, B., Bhakkan, B., Deloumeaux, J., du Plessis, M., Ekanem, I. A., Ekanem, U., Ezeome, E., Felix, N., Gachii, A. K., Gaete, S., Gibson, T., Hage, R., Harrison, S., Igbinoba, F., Iseh, K., Kiptanui, E., Korir, A., Lawson-Myers, H. D., Llanos, A., Luce, D., McNaughton, D., Odutola, M., Omonisi, A., Otu, T., Peruvien, J., Raheem, N., Roach, V., Sobers, N., Uamburu, N., & Ragin, C. (2021). Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3. Cancer epidemiology, 75102053. https://doi.org/10.1016/j.canep.2021.102053
Auguste, Aviane, et al. "Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3." Cancer epidemiology vol. 75 (2021): 102053. doi: https://doi.org/10.1016/j.canep.2021.102053
Auguste A, Gathere S, Pinheiro PS, Adebamowo C, Akintola A, Alleyne-Mike K, Anderson SG, Ashing K, Awittor FK, Awuah B, Bhakkan B, Deloumeaux J, du Plessis M, Ekanem IA, Ekanem U, Ezeome E, Felix N, Gachii AK, Gaete S, Gibson T, Hage R, Harrison S, Igbinoba F, Iseh K, Kiptanui E, Korir A, Lawson-Myers HD, Llanos A, Luce D, McNaughton D, Odutola M, Omonisi A, Otu T, Peruvien J, Raheem N, Roach V, Sobers N, Uamburu N, Ragin C. Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3. Cancer Epidemiol. 2021 Dec;75:102053. doi: 10.1016/j.canep.2021.102053. Epub 2021 Nov 04. PMID: 34743058; PMCID: PMC8627451.
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Cancer Epidemiol. 2021 Dec;75:102053. doi: 10.1016/j.canep.2021.102053. Epub 2021 Nov 04.

Heterogeneity in head and neck cancer incidence among black populations from Africa, the Caribbean and the USA: Analysis of cancer registry data by the AC3.

Cancer epidemiology

Aviane Auguste, Samuel Gathere, Paulo S Pinheiro, Clement Adebamowo, Adeola Akintola, Kellie Alleyne-Mike, Simon G Anderson, Kimlin Ashing, Fred Kwame Awittor, Baffour Awuah, Bernard Bhakkan, Jacqueline Deloumeaux, Maira du Plessis, Ima-Obong A Ekanem, Uwemedimbuk Ekanem, Emmanuel Ezeome, Nkese Felix, Andrew K Gachii, Stanie Gaete, Tracey Gibson, Robert Hage, Sharon Harrison, Festus Igbinoba, Kufre Iseh, Evans Kiptanui, Ann Korir, Heather-Dawn Lawson-Myers, Adana Llanos, Daniele Luce, Dawn McNaughton, Michael Odutola, Abidemi Omonisi, Theresa Otu, Jessica Peruvien, Nasiru Raheem, Veronica Roach, Natasha Sobers, Nguundja Uamburu, Camille Ragin

Affiliations

  1. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA. Electronic address: [email protected].
  2. The National Cancer Registry, Kenya Medical Research Institute, Nairobi, Kenya; African Caribbean Cancer Consortium USA.
  3. University of Miami, Sylvester Comprehensive Cancer Center, FL, USA; African Caribbean Cancer Consortium USA.
  4. Department of Epidemiology and Public Health and the Institute of Human Virology, The Marlene and Stewart Greenebaum Comprehensive Cancer Centre, University of Maryland School of Medicine, Baltimore, MD, USA; Center for Bioethics and Research, Ibadan, Nigeria; Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria.
  5. Center for Bioethics and Research, Ibadan, Nigeria; Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria.
  6. Cancer Centre of Trinidad and Tobago, St. James, Trinidad and Tobago; African Caribbean Cancer Consortium USA.
  7. Barbados National Registry, The George Alleyne Chronic Disease Research Centre, Caribbean Institute for Health Research, University of the West Indies, Cave Hill, Barbados; African Caribbean Cancer Consortium USA.
  8. City of Hope Cancer Center, Duarte, CA, USA; African Caribbean Cancer Consortium USA.
  9. Kumasi Cancer Registry, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
  10. Kumasi Cancer Registry, Komfo Anokye Teaching Hospital, Kumasi, Ghana; African Caribbean Cancer Consortium USA.
  11. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA.
  12. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France; Biological Resource Center Karubiotec™, BRIF n° KARUBIOTEC-GUA-00971, Pointe-à-Pitre, Guadeloupe; African Caribbean Cancer Consortium USA.
  13. Department of Anatomical Sciences, St Georges University, Grenada, West Indies; African Caribbean Cancer Consortium USA.
  14. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Calabar Cancer Registry, Department of Pathology, College of Medical Sciences, University of Calabar and Teaching Hospital, Calabar, Nigeria.
  15. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Community Health, Faculty of Clinical Sciences, College of Health Sciences, University of Uyo/University of Uyo Teaching Hospital, Uyo, Nigeria.
  16. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Enugu Cancer Registry, University of Nigeria Teaching Hospital, Enugu, Nigeria.
  17. Dr. Elizabeth Quamina Cancer Registry, the National Cancer Registry of Trinidad and Tobago, Mount Hope, Trinidad and Tobago.
  18. Department of Lab Medicine, Kenyatta National Hospital, Nairobi, Kenya; African Caribbean Cancer Consortium USA.
  19. Biological Resource Center Karubiotec™, BRIF n° KARUBIOTEC-GUA-00971, Pointe-à-Pitre, Guadeloupe; African Caribbean Cancer Consortium USA.
  20. Jamaica Cancer Registry, Department of Pathology, University of the West Indies, Kingston, Jamaica; African Caribbean Cancer Consortium USA.
  21. Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA; African Caribbean Cancer Consortium USA.
  22. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; National Hospital Abuja, Abuja, Nigeria.
  23. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Otorhinolaryngology/Head &Neck Surgery, Faculty of Clinical sciences, Usmanu Danfodiyo University/Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria; Population Based Cancer Registry, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
  24. The National Cancer Registry, Kenya Medical Research Institute, Nairobi, Kenya.
  25. Liguanea Family Dental Centre, Seymour Park, Kingston, Jamaica; African Caribbean Cancer Consortium USA.
  26. Department of Epidemiology, Mailman School of Public Health, Columbia University Irving Medical Center, New York, USA; African Caribbean Cancer Consortium USA.
  27. Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, Guadeloupe, France; African Caribbean Cancer Consortium USA.
  28. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Center for Big Data Research in Health, University of New South Wales, Sydney, Australia; African Caribbean Cancer Consortium USA.
  29. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Anatomic Pathology, Ekiti State University and Teaching Hospital, Ado-Ekiti, Nigeria.
  30. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Abuja Cancer Registry, Department of Haematology and Blood Transfusion, University of Abuja Teaching Hospital, Gawgwalada, Nigeria.
  31. Guadeloupe Cancer Registry, University Hospital of Guadeloupe, Pointe-à-Pitre, Guadeloupe, France.
  32. Nigerian National System of Cancer Registries, Federal Ministry of Health, Abuja, Nigeria; Department of Pathology, Federal Medical Centre, Yola, Nigeria.
  33. African Caribbean Cancer Consortium USA.
  34. Dental Department, Katutura State Hospital, Windhoek, Namibia; African Caribbean Cancer Consortium USA.

PMID: 34743058 PMCID: PMC8627451 DOI: 10.1016/j.canep.2021.102053

Abstract

BACKGROUND: Africa and the Caribbean are projected to have greater increases in Head and neck cancer (HNC) burden in comparison to North America and Europe. The knowledge needed to reinforce prevention in these populations is limited. We compared for the first time, incidence rates of HNC in black populations from African, the Caribbean and USA.

METHODS: Annual age-standardized incidence rates (IR) and 95% confidence intervals (95%CI) per 100,000 were calculated for 2013-2015 using population-based cancer registry data for 14,911 HNC cases from the Caribbean (Barbados, Guadeloupe, Trinidad & Tobago, N = 443), Africa (Kenya, Nigeria, N = 772) and the United States (SEER, Florida, N = 13,696). We compared rates by sub-sites and sex among countries using data from registries with high quality and completeness.

RESULTS: In 2013-2015, compared to other countries, HNC incidence was highest among SEER states (IR: 18.2, 95%CI = 17.6-18.8) among men, and highest in Kenya (IR: 7.5, 95%CI = 6.3-8.7) among women. Nasopharyngeal cancer IR was higher in Kenya for men (IR: 3.1, 95%CI = 2.5-3.7) and women (IR: 1.5, 95%CI = 1.0-1.9). Female oral cavity cancer was also notably higher in Kenya (IR = 3.9, 95%CI = 3.0-4.9). Blacks from SEER states had higher incidence of laryngeal cancer (IR: 5.5, 95%CI = 5.2-5.8) compared to other countries and even Florida blacks (IR: 4.4, 95%CI = 3.9-5.0).

CONCLUSION: We found heterogeneity in IRs for HNC among these diverse black populations; notably, Kenya which had distinctively higher incidence of nasopharyngeal and female oral cavity cancer. Targeted etiological investigations are warranted considering the low consumption of tobacco and alcohol among Kenyan women. Overall, our findings suggest that behavioral and environmental factors are more important determinants of HNC than race.

Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords: Africa; Alcohol drinking; Blacks; Caribbean; HPV; Head and neck cancer; Incidence; Population-based cancer registry; Tobacco smoking; USA

References

  1. Cancer Causes Control. 2017 Nov;28(11):1227-1239 - PubMed
  2. Cancer Causes Control. 2017 Nov;28(11):1173-1176 - PubMed
  3. BMC Psychiatry. 2015 Sep 25;15:230 - PubMed
  4. East Afr Med J. 2004 Jun;81(6):318-21 - PubMed
  5. Int J Cancer. 2019 Jul 1;145(1):99-109 - PubMed
  6. Pan Afr Med J. 2018 Jun 25;30:166 - PubMed
  7. Int J Cancer. 2017 Apr 15;140(8):1770-1780 - PubMed
  8. PLoS One. 2019 Sep 4;14(9):e0221334 - PubMed
  9. Cancer Med. 2020 Sep;9(18):6854-6863 - PubMed
  10. Cancer. 2007 Oct 1;110(7):1429-35 - PubMed
  11. Oral Oncol. 2014 May;50(5):387-403 - PubMed
  12. Cancer. 2018 May 15;124(10):2125-2133 - PubMed
  13. East Afr Med J. 1976 Feb;53(2):82-95 - PubMed
  14. Int J Mol Sci. 2017 Dec 19;18(12): - PubMed
  15. Prev Chronic Dis. 2019 Jun 27;16:E83 - PubMed
  16. Cancer Control. 2015 Oct;22(4):520-30 - PubMed
  17. Oral Oncol. 2009 Apr-May;45(4-5):309-16 - PubMed
  18. BMC Psychiatry. 2019 May 7;19(1):137 - PubMed
  19. MMWR Morb Mortal Wkly Rep. 2020 Jan 17;69(2):30-34 - PubMed
  20. BMC Public Health. 2019 Oct 30;19(1):1424 - PubMed
  21. Cancer Causes Control. 2017 Nov;28(11):1333-1340 - PubMed
  22. Cancer Causes Control. 2017 Nov;28(11):1241-1249 - PubMed
  23. Lancet Oncol. 2019 Sep;20(9):e503-e521 - PubMed
  24. J Oral Pathol Med. 2015 Apr;44(4):252-7 - PubMed
  25. CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90 - PubMed
  26. Oncology. 2016;91(1):13-23 - PubMed
  27. Ethn Health. 2021 Jul;26(5):659-675 - PubMed
  28. BMC Infect Dis. 2008 Aug 18;8:111 - PubMed
  29. Nat Rev Cancer. 2008 May;8(5):398-403 - PubMed
  30. BMC Public Health. 2018 Nov 7;18(Suppl 3):1223 - PubMed
  31. Curr Opin Oncol. 2013 Sep;25(5):503-10 - PubMed
  32. Cancer Control. 2016 Oct;23(4):347-358 - PubMed
  33. Oral Oncol. 2012 Jun;48(6):484-90 - PubMed
  34. Int J Occup Environ Med. 2015 Jul;6(3):129-43 - PubMed
  35. Cancer Epidemiol. 2020 Jun;66:101709 - PubMed
  36. PLoS One. 2016 Apr 06;11(4):e0152828 - PubMed
  37. Cancer Invest. 2008 Nov;26(9):936-47 - PubMed
  38. Cancer Epidemiol Biomarkers Prev. 2009 Feb;18(2):541-50 - PubMed
  39. Head Neck Oncol. 2009 May 28;1:14 - PubMed
  40. Lancet Oncol. 2014 Nov;15(12):1319-31 - PubMed

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