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Siddharthan T, Kalyesubula R, Morgan B, et al. The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey. BMC Public Health. 2021;21(1):2036doi: 10.1186/s12889-021-12123-7.
Siddharthan, T., Kalyesubula, R., Morgan, B., Ermer, T., Rabin, T. L., Kayongo, A., Munana, R., Anton, N., Kast, K., Schaeffner, E., Kirenga, B., Knauf, F. (2021). The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey. BMC public health, 21(1), 2036. https://doi.org/10.1186/s12889-021-12123-7
Siddharthan, Trishul, et al. "The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey." BMC public health vol. 21,1 (2021): 2036. doi: https://doi.org/10.1186/s12889-021-12123-7
Siddharthan T, Kalyesubula R, Morgan B, Ermer T, Rabin TL, Kayongo A, Munana R, Anton N, Kast K, Schaeffner E, Kirenga B, Knauf F. The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey. BMC Public Health. 2021 Nov 07;21(1):2036. doi: 10.1186/s12889-021-12123-7. PMID: 34743687; PMCID: PMC8572568.
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BMC Public Health. 2021 Nov 07;21(1):2036. doi: 10.1186/s12889-021-12123-7.

The rural Uganda non-communicable disease (RUNCD) study: prevalence and risk factors of self-reported NCDs from a cross sectional survey.

BMC public health

Trishul Siddharthan, Robert Kalyesubula, Brooks Morgan, Theresa Ermer, Tracy L Rabin, Alex Kayongo, Richard Munana, Nora Anton, Katharina Kast, Elke Schaeffner, Bruce Kirenga, Felix Knauf,

Affiliations

  1. Division of Pulmonary and Critical Care, School of Medicine, University of Miami, 1951 NW 7th Ave, Suite 2308, Miami, FL, 33136, USA. [email protected].
  2. Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. [email protected].
  3. Makerere College of Health Sciences, Makerere University, Kampala, Uganda.
  4. African Community Center for Social Sustainability (ACCESS), Nakaseke, Uganda.
  5. Division of Pulmonary and Critical Care, School of Medicine, University of Miami, 1951 NW 7th Ave, Suite 2308, Miami, FL, 33136, USA.
  6. Division of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
  7. Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
  8. Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
  9. Uganda Initiative for Integrated Management of Non-Communicable Diseases, Kampala, Uganda.
  10. World Health Summit c/o Charité Universitätsmedizin Berlin, Berlin, Germany.
  11. Department of Nephrology and Medical Intensive Care, Charité Universitätsmedizin Berlin, Berlin, Germany.
  12. Institute of Public Health, Charité Universitätsmedizin Berlin, Berlin, Germany.

PMID: 34743687 PMCID: PMC8572568 DOI: 10.1186/s12889-021-12123-7

Abstract

BACKGROUND: Non-communicable diseases (NCDs) are an increasing global concern, with morbidity and mortality largely occurring in low- and middle-income settings. We established the prospective Rural Uganda Non-Communicable Disease (RUNCD) cohort to longitudinally characterize the NCD prevalence, progression, and complications in rural Africa.

METHODS: We conducted a population-based census for NCD research. We systematically enrolled adults in each household among three sub-counties of the larger Nakaseke Health district and collected baseline demographic, health status, and self-reported chronic disease information. We present our data on self-reported chronic disease, as stratified by age, sex, educational attainment, and sub-county.

RESULTS: A total of 16,694 adults were surveyed with 10,563 (63%) respondents enrolled in the self-reported study. Average age was 37.8 years (SD = 16.5) and 45% (7481) were male. Among self-reported diseases, hypertension (HTN) was most prevalent (6.3%). 1.1% of participants reported a diagnosis of diabetes, 1.1% asthma, 0.7% COPD, and 0.4% kidney disease. 2.4% of the population described more than one NCD. Self-reported HTN was significantly higher in the peri-urban subcounty than in the other two rural sub-counties (p < 0.001); diagnoses for all other diseases did not differ significantly between sub-counties. Odds for self-reported HTN increased significantly with age (OR = 1.87 per 10 years of age, 95% CI 1.78-1.96). Male sex was associated with lower odds of reporting asthma (OR = 0.53, 95% CI 0.34-0.82) or HTN (OR = 0.31, 95% CI 0.26-0.40).

CONCLUSIONS: The RUNCD will establish one of the largest NCD patient cohorts in rural Africa. First analysis highlights the feasibility of systematically enrolling large numbers of adults living in a rural Ugandan district. In addition, our study demonstrates low levels of self-reported NCDs compared to the nation-wide established levels, emphasizing the need to better educate, characterize, and care for the majority of rural communities.

© 2021. The Author(s).

Keywords: Low- and middle-income countries; Non-communicable diseases; Rural

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