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Reddy RR, Reddy SG, Pandey A, et al. Effect of antibiotic pack on hard palate after fistula closure on nasal airflow and reoccurrence rate. J Oral Biol Craniofac Res. 2021;12(1):27-32doi: 10.1016/j.jobcr.2021.09.009.
Reddy, R. R., Reddy, S. G., Pandey, A., Banala, B., Bronkhorst, E. M., & Kuijpers-Jagtman, A. M. (2022). Effect of antibiotic pack on hard palate after fistula closure on nasal airflow and reoccurrence rate. Journal of oral biology and craniofacial research, 12(1), 27-32. https://doi.org/10.1016/j.jobcr.2021.09.009
Reddy, Rajgopal R, et al. "Effect of antibiotic pack on hard palate after fistula closure on nasal airflow and reoccurrence rate." Journal of oral biology and craniofacial research vol. 12,1 (2022): 27-32. doi: https://doi.org/10.1016/j.jobcr.2021.09.009
Reddy RR, Reddy SG, Pandey A, Banala B, Bronkhorst EM, Kuijpers-Jagtman AM. Effect of antibiotic pack on hard palate after fistula closure on nasal airflow and reoccurrence rate. J Oral Biol Craniofac Res. 2022 Jan-Feb;12(1):27-32. doi: 10.1016/j.jobcr.2021.09.009. Epub 2021 Sep 30. PMID: 34745861; PMCID: PMC8556516.
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J Oral Biol Craniofac Res. 2022 Jan-Feb;12(1):27-32. doi: 10.1016/j.jobcr.2021.09.009. Epub 2021 Sep 30.

Effect of antibiotic pack on hard palate after fistula closure on nasal airflow and reoccurrence rate.

Journal of oral biology and craniofacial research

Rajgopal R Reddy, Srinivas Gosla Reddy, Avni Pandey, Bhavya Banala, Ewald M Bronkhorst, Anne Marie Kuijpers-Jagtman

Affiliations

  1. Cranio-maxillofacial Surgery, G.S.R. Hospital, Institute of Cranio-Maxillofacial and Facial Plastic Surgery, Vinay Nagar Colony, Saidabad, Hyderabad, India.
  2. G.S.R. Hospital, Institute of Cranio-Maxillofacial and Facial Plastic Surgery, Vinay Nagar Colony, Saidabad, Hyderabad, India.
  3. Speech and Language Therapy,G.S.R. Hospital, Institute of Cranio-Maxillofacial and Facial Plastic Surgery, Vinay Nagar Colony, Saidabad, Hyderabad, India.
  4. Department of Cariology and Preventive Dentistry, Radboud University Medical Center, Nijmegen, the Netherlands.
  5. Department of Orthodontics, University Medical Centre Groningen Groningen, the Netherlands.

PMID: 34745861 PMCID: PMC8556516 DOI: 10.1016/j.jobcr.2021.09.009

Abstract

This parallel blocked randomized controlled trial was done in two groups of 30 patients each to determine if placement of an antibiotic oral pack on the hard palate after hard palatal fistula repair reduces nasal air emission and fistula re-occurrence. Group A had an oral pack on the hard palate for 5 days post-operatively while group B did not. In group A, percentage of nasal air emission was tested using nasometry with and without pack. Paired t-tests were performed to compare nasal emissions for patients with and without pack. Recurrence of fistulas after 6 months between group A and B was tested using odds ratio. Effect of nasal air emission on fistula rates was tested using paired t-tests. There was a significant increase (p < 0.0001) in nasal emission after removal of the pack in group A. Fistula re-occurrence tended to be higher in group B (no pack) than group A but this was not significant (p = 0.242). There was no correlation between nasal air emission and fistula rates. In patients with recurrent fistulae, placement of an oral pack after fistula repair diminishes nasal air emission. Whether this has an impact on re-occurrence of fistulae needs to be investigated further.

© 2021 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.

Keywords: Cleft palate; Operative; Oral fistula; Surgical procedures; Treatment outcome

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