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Infect Agent Cancer. 2021 Oct 30;16(1):62. doi: 10.1186/s13027-021-00401-3.

Strategies to evaluate outcomes in long-COVID-19 and post-COVID survivors.

Infectious agents and cancer

Anna Crispo, Sabrina Bimonte, Giuseppe Porciello, Cira Antonietta Forte, Gaia Cuomo, Concetta Montagnese, Melania Prete, Maria Grimaldi, Egidio Celentano, Alfonso Amore, Elvio de Blasio, Francesca Pentimalli, Antonio Giordano, Gerardo Botti, Giovanni Baglio, Pierpaolo Sileri, Marco Cascella, Arturo Cuomo

Affiliations

  1. Epidemiology and Biostatistics Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
  2. Division of Anesthesia and Pain Medicine, Istituto Nazionale dei Tumori Fondazione G. Pascale, 80131, Naples, Italy. [email protected].
  3. Division of Anesthesia and Pain Medicine, Istituto Nazionale dei Tumori Fondazione G. Pascale, 80131, Naples, Italy.
  4. SSD Chirurgia Melanoma E Dei Tumori Cutanei, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
  5. Multidisciplinary Emergency Unit for COVID-19 Campania, 80100, Naples, Italy.
  6. Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131, Naples, Italy.
  7. Ministry of Health, 00153, Rome, Italy.
  8. Center for Biotechnology, College of Science and Technology, Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, PA, 19122, USA.
  9. Scientific Direction, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Naples, Italy.
  10. Head of the Unit "Research and International Relations", Italian National Agency for Regional Health Services - AGENAS, 00187, Rome, Italy.
  11. Università Vita Salute San Raffaele, 20132, Milan, Italy.

PMID: 34717691 PMCID: PMC8556851 DOI: 10.1186/s13027-021-00401-3

Abstract

SARS-CoV-2 infection can impact the physical, cognitive, mental health of patients, especially in those recovered in intensive care units. Moreover, it was proved that the effects of the virus may persist for weeks or months. The term long-COVID or post-COVID syndrome is commonly used for indicating a variety of physical and psychological symptoms that continue after the resolution of the acute phase. This narrative review is aimed at providing an updated overview of the impact of physical, cognitive, and psychological health disorders in COVID-19 survivors, by summarizing the data already published in literature in the last year. Studies cited were found through PubMed searches. We also presented an overview of the post-COVID-19 health consequences on three important aspects: nutritional status, neurological disorders, and physical health. Moreover, to activate a correct health planning policy, a multidisciplinary approach for addressing the post- COVID-19 issue, has been proposed. Finally, the involvement of health professionals is necessary even after the pandemic, to reduce expected post-pandemic psychosocial responses and mental health disorders.

© 2021. The Author(s).

Keywords: COVID-19 pandemic; Intensive care units; Neurocognitive disorders; Public health

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