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Ginige S, Daly J, Hyland C, et al. The role of non-invasive prenatal testing (NIPT) for fetal blood group typing in Australia. Aust N Z J Obstet Gynaecol. 2021;doi: 10.1111/ajo.13446.
Ginige, S., Daly, J., Hyland, C., Powley, T., O'Brien, H., Moreno, A. M., Gardener, G., & Flower, R. (2021). The role of non-invasive prenatal testing (NIPT) for fetal blood group typing in Australia. The Australian & New Zealand journal of obstetrics & gynaecology, . https://doi.org/10.1111/ajo.13446
Ginige, Shamila, et al. "The role of non-invasive prenatal testing (NIPT) for fetal blood group typing in Australia." The Australian & New Zealand journal of obstetrics & gynaecology vol. (2021). doi: https://doi.org/10.1111/ajo.13446
Ginige S, Daly J, Hyland C, Powley T, O'Brien H, Moreno AM, Gardener G, Flower R. The role of non-invasive prenatal testing (NIPT) for fetal blood group typing in Australia. Aust N Z J Obstet Gynaecol. 2021 Oct 18; doi: 10.1111/ajo.13446. Epub 2021 Oct 18. PMID: 34661280.
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Aust N Z J Obstet Gynaecol. 2021 Oct 18; doi: 10.1111/ajo.13446. Epub 2021 Oct 18.

The role of non-invasive prenatal testing (NIPT) for fetal blood group typing in Australia.

The Australian & New Zealand journal of obstetrics & gynaecology

Shamila Ginige, James Daly, Catherine Hyland, Tanya Powley, Helen O'Brien, Ana M Moreno, Glenn Gardener, Robert Flower

Affiliations

  1. Australian Red Cross Lifeblood, Brisbane, Queensland, Australia.
  2. Mater Centre for Maternal Fetal Medicine, Brisbane, Queensland, Australia.
  3. Mater Research Institute at the University of Queensland, Brisbane, Queensland, Australia.

PMID: 34661280 DOI: 10.1111/ajo.13446

Abstract

Maternal alloimmunisation against red blood cell antigens can cause haemolytic disease of the fetus and newborn (HDFN). Although most frequently caused by anti-D, since the implementation of rhesus D (RhD) immunoglobulin prophylaxis, other alloantibodies have become more prevalent in HDFN. Recent advances in non-invasive prenatal testing (NIPT) have allowed early prediction of HDFN risk in alloimmunised pregnancies and allow clinicians to focus health resources on those pregnancies that require intervention. This article aims to provide updates on the current status of NIPT in Australia as both a diagnostic and screening tool in pregnancy.

© 2021 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

Keywords: Australia; alloantibodies; fetal blood group; haemolytic disease of the fetus and newborn; prenatal testing

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