Display options
Cite
Kovalainen A, Haeren R, Paetau A, et al. Brainstem intraparenchymal schwannoma: A case report and literature review. Surg Neurol Int. 2021;12:508doi: 10.25259/SNI_621_2021.
Kovalainen, A., Haeren, R., Paetau, A., Lehecka, M., Bryan, A., & Mayock, P. (2021). Brainstem intraparenchymal schwannoma: A case report and literature review. Surgical neurology international, 12508. https://doi.org/10.25259/SNI_621_2021
Kovalainen, Anselmi, et al. "Brainstem intraparenchymal schwannoma: A case report and literature review." Surgical neurology international vol. 12 (2021): 508. doi: https://doi.org/10.25259/SNI_621_2021
Kovalainen A, Haeren R, Paetau A, Lehecka M, Bryan A, Mayock P. Brainstem intraparenchymal schwannoma: A case report and literature review. Surg Neurol Int. 2021 Oct 11;12:508. doi: 10.25259/SNI_621_2021. eCollection 2021. PMID: 34754558; PMCID: PMC8571199.
Copy Download .nbib Format: NLM
Share it on

Surg Neurol Int. 2021 Oct 11;12:508. doi: 10.25259/SNI_621_2021. eCollection 2021.

Brainstem intraparenchymal schwannoma: A case report and literature review.

Surgical neurology international

Anselmi Kovalainen, Roel Haeren, Anders Paetau, Martin Lehecka, Bryan, Mayock

Affiliations

  1. Department of Neurosurgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
  2. Department of Neurosurgery, Maastricht University Medical Center, Maastricht, Netherlands.
  3. Department of Pathology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

PMID: 34754558 PMCID: PMC8571199 DOI: 10.25259/SNI_621_2021

Abstract

BACKGROUND: Intracranial intraparenchymal schwannomas (IS) are rare tumors that have mainly been described in case reports. Here, we report on a case of a brainstem IS and included a comprehensive literature review.

CASE DESCRIPTION: A 74-year-old man presented with progressive gait disturbances. CT- and MRI-imaging revealed a contrast-enhancing mass accompanied by a cyst in the dorsolateral pons. Hemangioblastoma was suspected and surgery was advised. During surgery, gross total resection of a non-invasive tumor was performed. Postoperative recovery was uneventful. Based on histopathological examination, the intraparenchymal brainstem tumor was diagnosed as schwannoma.

CONCLUSION: Our extensive review illustrates that ISs are benign tumors that most often present in relatively young patients. Malignant cases have been described but form an extremely rare entity. Preoperative diagnosis based on radiological features is difficult but should be considered when peritumoral edema, calcifications, and cysts are noted. In benign cases, gross total resection of the lesion is curative. To adequately select this treatment and adjust the surgical strategy accordingly, it is important to include IS in the preoperative differential diagnosis when the abovementioned radiological features are present.

Copyright: © 2021 Surgical Neurology International.

Keywords: Brainstem; Case report; Intraparenchymal; Review; Schwannoma; Tumor

Conflict of interest statement

There are no conflicts of interest.

References

  1. J Neurosurg. 2003 Mar;98(3):621-4 - PubMed
  2. J Neurosurg. 1966 Feb;24(2):552-7 - PubMed
  3. Case Rep Surg. 2013;2013:384076 - PubMed
  4. Neurol Med Chir (Tokyo). 2012;52(8):603-7 - PubMed
  5. J Neurol. 2007 Aug;254(8):1009-11 - PubMed
  6. Turk Neurosurg. 2009 Jan;19(1):82-5 - PubMed
  7. J Clin Neurosci. 2011 Mar;18(3):411-3 - PubMed
  8. Acta Neurochir (Wien). 1997;139(8):756-60 - PubMed
  9. Neurol India. 2012 May-Jun;60(3):335-7 - PubMed
  10. Neurosurgery. 2006 Aug;59(2):354-9; discussion 354-9 - PubMed
  11. Clin Neurol Neurosurg. 2013 Jul;115(7):1052-7 - PubMed
  12. Surg Neurol. 1989 Aug;32(2):156-8 - PubMed
  13. Clin Neurol Neurosurg. 2012 Jan;114(1):42-6 - PubMed
  14. Medicine (Baltimore). 2019 Jan;98(4):e14263 - PubMed
  15. World Neurosurg. 2017 Feb;98:873.e1-873.e7 - PubMed
  16. J Neurosurg. 1993 Aug;79(2):217-22 - PubMed
  17. Acta Neurol Belg. 2008 Jun;108(2):67-71 - PubMed
  18. Neurosurg Rev. 1996;19(4):269-74 - PubMed
  19. Radiographics. 2016 Sep-Oct;36(5):1463-77 - PubMed
  20. AJNR Am J Neuroradiol. 2010 Mar;31(3):567-9 - PubMed
  21. Br J Neurosurg. 1993;7(4):427-9 - PubMed
  22. Surg Neurol. 1984 Jul;22(1):69-72 - PubMed

Publication Types