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Bouwmeester S, Mast TP, Keulards DCJ, et al. Left atrial reverse remodeling predicts long-term survival after cardiac resynchronization therapy. J Echocardiogr. 2021;doi: 10.1007/s12574-021-00559-0.
Bouwmeester, S., Mast, T. P., Keulards, D. C. J., de Lepper, A. G. W., Herold, I. H. F., Dekker, L. R., Prinzen, F. W., & Houthuizen, P. (2021). Left atrial reverse remodeling predicts long-term survival after cardiac resynchronization therapy. Journal of echocardiography, . https://doi.org/10.1007/s12574-021-00559-0
Bouwmeester, Sjoerd, et al. "Left atrial reverse remodeling predicts long-term survival after cardiac resynchronization therapy." Journal of echocardiography vol. (2021). doi: https://doi.org/10.1007/s12574-021-00559-0
Bouwmeester S, Mast TP, Keulards DCJ, de Lepper AGW, Herold IHF, Dekker LR, Prinzen FW, Houthuizen P. Left atrial reverse remodeling predicts long-term survival after cardiac resynchronization therapy. J Echocardiogr. 2021 Nov 25; doi: 10.1007/s12574-021-00559-0. Epub 2021 Nov 25. PMID: 34822132.
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J Echocardiogr. 2021 Nov 25; doi: 10.1007/s12574-021-00559-0. Epub 2021 Nov 25.

Left atrial reverse remodeling predicts long-term survival after cardiac resynchronization therapy.

Journal of echocardiography

Sjoerd Bouwmeester, Thomas P Mast, Daniëlle C J Keulards, Anouk G W de Lepper, Ingeborg H F Herold, Lukas R Dekker, Frits W Prinzen, Patrick Houthuizen

Affiliations

  1. Department of Cardiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands. [email protected].
  2. Department of Cardiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.
  3. Department of Anesthesiology and Intensive Care, Catharina Hospital, Eindhoven, The Netherlands.
  4. Department of Electrical Engineering, Technical University, Eindhoven, The Netherlands.
  5. Department of Physiology, School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.

PMID: 34822132 DOI: 10.1007/s12574-021-00559-0

Abstract

BACKGROUND: Left ventricular (LV) reverse remodeling has been identified as a strong predictor of long-term survival in patients receiving CRT. Interestingly, CRT induces reverse remodeling in the left atrium (LA) as well. It is currently unknown to what extent LA reverse remodeling is correlated to long-term survival after CRT. This study aims to assess the long-term prognostic value of left atrium (LA) reverse remodeling in patients undergoing cardiac resynchronization therapy (CRT).

METHODS: Baseline and 3-months follow-up echocardiograms after CRT implantation were prospectively assessed to determine changes in left ventricular end-systolic volume (LVESV), left ventricular ejection fraction (LVEF), left atrial volume (LAV), and left atrial reservoir strain (LAS

RESULTS: In our study population of 99 patients with a mean follow-up of 6.3 ± 2.1 years, 43 patients (43%) reached the end-point of all-cause mortality. More extensive LA reverse remodeling, as measured by a relative increase in LAS

CONCLUSION: An increase in LAS

© 2021. Japanese Society of Echocardiography.

Keywords: Bundle branch block; Cardiac resynchronization therapy; Heart failure; Left atrial reverse remodeling; Left atrial strain; Left ventricular reverse remodeling

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