Display options
Cite
Tharakan T, Khoo CC, Giwercman A, et al. Are sex disparities in COVID-19 a predictable outcome of failing men's health provision?. Nat Rev Urol. 2021;doi: 10.1038/s41585-021-00535-4.
Tharakan, T., Khoo, C. C., Giwercman, A., Jayasena, C. N., Sofikitis, N., Salonia, A., & Minhas, S. (2021). Are sex disparities in COVID-19 a predictable outcome of failing men's health provision?. Nature reviews. Urology, . https://doi.org/10.1038/s41585-021-00535-4
Tharakan, Tharu, et al. "Are sex disparities in COVID-19 a predictable outcome of failing men's health provision?." Nature reviews. Urology vol. (2021). doi: https://doi.org/10.1038/s41585-021-00535-4
Tharakan T, Khoo CC, Giwercman A, Jayasena CN, Sofikitis N, Salonia A, Minhas S. Are sex disparities in COVID-19 a predictable outcome of failing men's health provision?. Nat Rev Urol. 2021 Nov 18; doi: 10.1038/s41585-021-00535-4. Epub 2021 Nov 18. PMID: 34795426; PMCID: PMC8600906.
Copy Download .nbib Format: NLM
Share it on

Nat Rev Urol. 2021 Nov 18; doi: 10.1038/s41585-021-00535-4. Epub 2021 Nov 18.

Are sex disparities in COVID-19 a predictable outcome of failing men's health provision?.

Nature reviews. Urology

Tharu Tharakan, Christopher C Khoo, Aleksander Giwercman, Channa N Jayasena, Nikolaos Sofikitis, Andrea Salonia, Suks Minhas

Affiliations

  1. Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK. [email protected].
  2. Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK. [email protected].
  3. Department of Urology, Imperial Healthcare NHS Trust, Charing Cross Hospital, London, UK.
  4. Department of Translational Medicine, Lund University, Lund, Sweden.
  5. Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
  6. Department of Urology, Ioannina University School of Medicine, Ioannina, Greece.
  7. Division of Experimental Oncology/Unite of Urology, URI, IRCCS Ospedale, San Raffaele, Milan, Italy.
  8. University Vita-Salute San Raffaele, Milan, Italy.
  9. Department of Surgery and Cancer, Imperial College London, London, UK.

PMID: 34795426 PMCID: PMC8600906 DOI: 10.1038/s41585-021-00535-4

Abstract

The COVID-19 pandemic, caused by the SARS-CoV-2 coronavirus, has taken a catastrophic toll on society, health-care systems and the economy. Notably, COVID-19 has been shown to be associated with a higher mortality rate in men than in women. This disparity is likely to be a consequence of a failure to invest in men's health, as it has also been established that men have a lower life expectancy and poorer outcomes from non-communicable diseases than women. A variety of biological, social and economic factors have contributed to the sex disparities in mortality from COVID-19. A streamlined men's health programme - with the urologist as the gatekeeper of men's health - is needed to help prevent future tragedies of this nature.

© 2021. The Author(s), under exclusive licence to Springer Nature Limited.

References

  1. Vaccine. 2006 Mar 20;24(13):2395-402 - PubMed
  2. Lancet. 2016 Apr 9;387(10027):1513-1530 - PubMed
  3. Br J Cancer. 2009 Dec 3;101 Suppl 2:S18-23 - PubMed
  4. Diabetologia. 2001 Jan;44(1):3-15 - PubMed
  5. Int J Comp Sociol. 2006 Dec;47(6):466-487 - PubMed
  6. Nature. 2020 Mar;579(7798):270-273 - PubMed
  7. Am J Med. 1994 May;96(5):457-62 - PubMed
  8. BMJ. 2014 Nov 17;349:g5992 - PubMed
  9. Lancet. 2020 Feb 22;395(10224):565-574 - PubMed
  10. Clin Microbiol Infect. 2020 Jun;26(6):767-772 - PubMed
  11. Plast Surg Int. 2015;2015:747961 - PubMed
  12. J Natl Cancer Inst. 2016 May 06;108(10): - PubMed
  13. J Public Health (Oxf). 2008 Mar;30(1):111-3 - PubMed
  14. Cancer Pract. 1995 Sep-Oct;3(5):310-6 - PubMed
  15. Obesity (Silver Spring). 2007 Dec;15(12):2984-93 - PubMed
  16. Circulation. 2011 May 31;123(21):e609-11 - PubMed
  17. Lancet. 2018 Nov 10;392(10159):1684-1735 - PubMed
  18. Soc Sci Med. 1999 May;48(10):1363-72 - PubMed
  19. Am J Public Health. 2003 Jun;93(6):939-42 - PubMed
  20. Can J Cardiol. 2020 Jun;36(6):915-930 - PubMed
  21. Life Sci. 2006 Apr 4;78(19):2166-71 - PubMed
  22. Lancet Public Health. 2019 Nov;4(11):e553-e564 - PubMed
  23. J Infect Dis. 2014 Jul 15;209 Suppl 3:S79-80 - PubMed
  24. BMJ. 2000 Sep 30;321(7264):789-92 - PubMed
  25. Lancet. 2019 Feb 9;393(10171):550-559 - PubMed
  26. Am J Mens Health. 2017 Nov;11(6):1804-1808 - PubMed
  27. Clin Exp Immunol. 2003 May;132(2):265-70 - PubMed
  28. BMC Public Health. 2009 Jun 30;9:213 - PubMed
  29. Cells. 2020 Apr 09;9(4): - PubMed
  30. Hum Reprod. 2001 May;16(5):972-8 - PubMed
  31. Lancet. 2017 Feb 25;389(10071):815-822 - PubMed
  32. Int J Impot Res. 2020 Nov;32(6):565-568 - PubMed
  33. Am J Obstet Gynecol. 1981 Jan;139(1):47-51 - PubMed
  34. N Engl J Med. 2020 Apr 30;382(18):1708-1720 - PubMed
  35. J Urol. 2020 Mar;203(3):486-495 - PubMed
  36. Lancet. 2020 Mar 28;395(10229):1054-1062 - PubMed
  37. J Epidemiol Community Health. 2007 Dec;61(12):1086-90 - PubMed
  38. Circ Cardiovasc Qual Outcomes. 2013 Jan 1;6(1):99-109 - PubMed
  39. Hum Reprod. 2014 Jul;29(7):1567-74 - PubMed
  40. J Immunol. 2017 May 15;198(10):4046-4053 - PubMed
  41. Med Care. 1981 Jun;19(6):609-32 - PubMed
  42. Br J Health Psychol. 2010 Nov;15(Pt 4):921-39 - PubMed
  43. Nature. 2003 Nov 27;426(6965):450-4 - PubMed
  44. Eur Urol. 2009 Dec;56(6):1025-31 - PubMed
  45. Int J Environ Res Public Health. 2020 Mar 30;17(7): - PubMed
  46. Arch Intern Med. 2008 Dec 8;168(22):2405-14 - PubMed
  47. J Infect Dis. 2014 Jul 15;209 Suppl 3:S93-9 - PubMed
  48. Prog Community Health Partnersh. 2019;13(5):137-142 - PubMed
  49. CA Cancer J Clin. 2021 May;71(3):209-249 - PubMed
  50. Nat Rev Urol. 2020 May;17(5):251-253 - PubMed
  51. World Psychiatry. 2005 Jun;4(2):114-20 - PubMed
  52. Cancer Discov. 2014 Nov;4(11):1310-25 - PubMed
  53. Drug Dev Res. 2020 Nov;81(7):771-776 - PubMed
  54. BMJ. 2018 Nov 7;363:k4247 - PubMed
  55. Am J Prev Med. 2004 Aug;27(2):97-105 - PubMed
  56. Eur Heart J. 2020 May 14;41(19):1810-1817 - PubMed
  57. BMC Fam Pract. 2016 Mar 31;17:38 - PubMed
  58. Crit Rev Immunol. 2012;32(1):23-63 - PubMed
  59. Nephron. 2020;144(5):213-221 - PubMed
  60. Diabetes Care. 2011 Apr;34(4):828-37 - PubMed
  61. Int J Obes (Lond). 2008 Jun;32(6):949-58 - PubMed
  62. J Immunol. 2011 Jun 1;186(11):6465-73 - PubMed
  63. Curr Opin Psychol. 2015 Oct;5:78-84 - PubMed
  64. BMJ Open. 2013 Aug 19;3(8):e003320 - PubMed
  65. Ann N Y Acad Sci. 1999 Jun 22;876:426-9 - PubMed
  66. BMJ Glob Health. 2017 Mar 27;2(2):e000298 - PubMed
  67. Clin Psychol Rev. 2016 Nov;49:106-118 - PubMed
  68. Menopause. 2009 Jan-Feb;16(1):15-23 - PubMed
  69. Diabetologia. 1992 Jan;35(1):56-62 - PubMed
  70. Cell Immunol. 2012;272(2):214-9 - PubMed
  71. Am J Clin Nutr. 1994 Jun;59(6):1277-85 - PubMed
  72. J Med Virol. 2020 Nov;92(11):2304-2305 - PubMed
  73. BMC Int Health Hum Rights. 2012 Nov 06;12:28 - PubMed
  74. Diabetologia. 2011 Dec;54(12):3003-6 - PubMed
  75. Inflammation. 2013 Dec;36(6):1503-12 - PubMed
  76. Eur Respir J. 2020 Apr 16;55(4): - PubMed
  77. Eur Urol. 2019 Dec;76(6):712-713 - PubMed
  78. Lancet. 2016 Apr 2;387(10026):1377-1396 - PubMed
  79. Expert Opin Drug Saf. 2014 Oct;13(10):1361-74 - PubMed
  80. Circulation. 2019 Mar 5;139(10):e56-e528 - PubMed
  81. Behav Med. 2016 Jul-Sep;42(3):211-5 - PubMed
  82. N Engl J Med. 1979 Feb 1;300(5):213-7 - PubMed
  83. Public Health. 2011 Jul;125(7):417-23 - PubMed
  84. J Virol. 2001 Mar;75(6):3048-52 - PubMed
  85. Eur Urol. 2020 Dec;78(6):786-811 - PubMed
  86. Clin Mol Allergy. 2012 Jan 04;10(1):2 - PubMed
  87. J Med Virol. 2020 Oct;92(10):1759-1760 - PubMed
  88. Nat Rev Immunol. 2016 Oct;16(10):626-38 - PubMed
  89. Pharmacol Res. 2020 Aug;158:104931 - PubMed
  90. Fertil Steril. 2013 Sep;100(3):681-5 - PubMed
  91. Cell Death Dis. 2020 Jun 8;11(6):438 - PubMed
  92. Nature. 2020 Aug;584(7821):430-436 - PubMed
  93. Int J Chron Obstruct Pulmon Dis. 2018 May 10;13:1507-1514 - PubMed
  94. J Clin Endocrinol Metab. 2004 Jul;89(7):3313-8 - PubMed
  95. Eur Heart J. 2008 Apr;29(7):932-40 - PubMed
  96. Int J Clin Pract. 2010 Mar;64(4):475-87 - PubMed
  97. J Immunol. 2006 Aug 15;177(4):2088-96 - PubMed
  98. Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7993-8 - PubMed
  99. J Leukoc Biol. 2014 Mar;95(3):497-507 - PubMed
  100. JMIR Mhealth Uhealth. 2019 Apr 15;7(4):e10216 - PubMed
  101. Med Care. 1988 Jul;26(7):657-75 - PubMed
  102. BMC Fam Pract. 2012 May 28;13:44 - PubMed
  103. JAMA. 2020 May 12;323(18):1775-1776 - PubMed
  104. N Engl J Med. 2010 Mar 25;362(12):1090-101 - PubMed
  105. Crit Care Resusc. 2020 Apr 15;22(2):95-97 - PubMed
  106. Am J Epidemiol. 2002 Feb 15;155(4):354-60 - PubMed
  107. N Engl J Med. 2018 May 10;378(19):1767-1777 - PubMed
  108. Lancet. 2020 Feb 15;395(10223):497-506 - PubMed
  109. Andrology. 2021 Jan;9(1):99-106 - PubMed
  110. Lancet. 2019 Jul 20;394(10194):198-199 - PubMed
  111. Mol Med Rep. 2020 Jul;22(1):20-32 - PubMed
  112. Nat Rev Urol. 2015 Nov;12(11):599-600 - PubMed
  113. Lancet Diabetes Endocrinol. 2020 Oct;8(10):813-822 - PubMed
  114. J Med Virol. 2020 Oct;92(10):1915-1921 - PubMed
  115. Aust J Rural Health. 2006 Jun;14(3):129-31 - PubMed
  116. Lancet. 2020 Jun 6;395(10239):1763-1770 - PubMed
  117. J Gen Intern Med. 2021 Jan;36(1):17-26 - PubMed
  118. J Urol. 2000 Feb;163(2):460-3 - PubMed
  119. J Urol. 2013 Jan;189(1 Suppl):S107-14; discussion S115-6 - PubMed
  120. Obesity (Silver Spring). 2020 Jul;28(7):1195-1199 - PubMed
  121. Andrologia. 2014 Mar;46(2):167-76 - PubMed
  122. Hum Immunol. 2004 May;65(5):476-85 - PubMed
  123. J Clin Med. 2020 Nov 26;9(12): - PubMed
  124. Am J Public Health. 2001 Oct;91(10):1686-93 - PubMed
  125. Eur Urol Focus. 2020 Jul 15;6(4):791-800 - PubMed
  126. Ann Ist Super Sanita. 2016 Apr-Jun;52(2):198-204 - PubMed
  127. Vaccine. 2009 May 26;27(25-26):3319-23 - PubMed
  128. Public Health. 2015 Jan;129(1):60-7 - PubMed
  129. CA Cancer J Clin. 2018 Nov;68(6):394-424 - PubMed
  130. N Engl J Med. 2006 Feb 16;354(7):719-30 - PubMed
  131. Am J Mens Health. 2019 Oct;13(5):1557988319873532 - PubMed
  132. Oncotarget. 2018 Apr 3;9(25):17420-17429 - PubMed
  133. Cell. 2020 Apr 16;181(2):271-280.e8 - PubMed
  134. Biol Sex Differ. 2011 Aug 01;2:8 - PubMed
  135. N Engl J Med. 1999 Jun 10;340(23):1801-11 - PubMed
  136. J Autoimmun. 2020 Aug;112:102463 - PubMed
  137. Int J Tuberc Lung Dis. 2008 Jul;12(7):703-8 - PubMed
  138. Eur Urol. 2020 Jul;78(1):21-28 - PubMed
  139. J Hypertens. 2001 Dec;19(12):2205-12 - PubMed
  140. J Med Virol. 2020 Jul;92(7):797-806 - PubMed
  141. Lancet. 2007 Mar 3;369(9563):750-756 - PubMed
  142. Gut. 2012 Oct;61(10):1439-46 - PubMed
  143. Eur Respir J. 2020 May 7;55(5): - PubMed
  144. BMJ. 2020 May 22;369:m1985 - PubMed
  145. J Sex Med. 2015 Apr;12(4):975-84 - PubMed
  146. Diabetes Care. 2002 Jan;25(1):55-60 - PubMed
  147. Diabetes. 2011 Jan;60(1):56-63 - PubMed

Publication Types