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Sports Med. 2021 Nov 19; doi: 10.1007/s40279-021-01588-6. Epub 2021 Nov 19.

ICON 2020-International Scientific Tendinopathy Symposium Consensus: A Systematic Review of Outcome Measures Reported in Clinical Trials of Achilles Tendinopathy.

Sports medicine (Auckland, N.Z.)

Karin Grävare Silbernagel, Peter Malliaras, Robert-Jan de Vos, Shawn Hanlon, Mitchel Molenaar, Håkan Alfredson, Inge van den Akker-Scheek, Jarrod Antflick, Mathijs van Ark, Kenneth Färnqvist, Zubair Haleem, Jean-Francois Kaux, Paul Kirwan, Bhavesh Kumar, Trevor Lewis, Adrian Mallows, Lorenzo Masci, Dylan Morrissey, Myles Murphy, Richard Newsham-West, Richard Norris, Seth O'Neill, Koen Peers, Igor Sancho, Kayla Seymore, Patrick Vallance, Arco van der Vlist, Bill Vicenzino

Affiliations

  1. Department of Physical Therapy, University of Delaware, 540 South College Avenue, Newark, DE, 19713, USA. [email protected].
  2. Physiotherapy Department, School of Primary and Allied Health Care, Faculty of Medicine Nursing and Health Science, Monash University, Melbourne, VIC, Australia.
  3. Department of Orthopaedic Surgery and Sports Medicine, Erasmus MC University Medical Centre, Rotterdam, Zuid-Holland, The Netherlands.
  4. Department of Physical Therapy, University of Delaware, 540 South College Avenue, Newark, DE, 19713, USA.
  5. Department of Cardiology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
  6. Department of Community Medicine and Rehabilitation, Rehabilitation Medicine, Umeå University, Umeå, Sweden.
  7. Department of Orthopedics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
  8. Department of Bioengineering, School of Engineering, Imperial College, London, UK.
  9. Department of Physiotherapy, School of Health Care Studies, Hanze University of Applied Sciences and Peescentrum, Centre of Expertise Primary Care Groningen (ECEZG), Groningen, The Netherlands.
  10. , Stockholm, Sweden.
  11. Sports and Exercise Medicine, Queen Mary University of London, London, UK.
  12. Arsenal Football Club, London, UK.
  13. Department of Physical and Rehabilitation Medicine and Sports Traumatology, University and University Hospital of Liège, Liège, Belgium.
  14. School of Physiotherapy, Royal College of Surgeons in Ireland, Dublin, Ireland.
  15. Institute of Sport Exercise and Health (ISEH), University College London, London, UK.
  16. Aintree University Hospital, Liverpool Foundation Trust, Liverpool, UK.
  17. School of Sport, Rehabilitation and Exercise Sciences, University of Essex, Colchester, UK.
  18. National School of Nursing, Midwifery, Health Sciences and Physiotherapy, The University of Notre Dame Australia, Fremantle, WA, Australia.
  19. School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  20. School of Allied Health, Department of Physiotherapy, La Trobe University, Melbourne, VIC, Australia.
  21. Liverpool University Hospitals, NHS Foundation Trust, Liverpool, UK.
  22. School of Allied Health, University of Leicester, Leicester, UK.
  23. Department of Physical and Rehabilitation Medicine, University Hospitals Leuven, Leuven, Belgium.
  24. Physiotherapy Department, University of Deusto, San Sebastian, Spain.
  25. Physiotherapy Department, School of Primary and Allied Health Care, Faculty of Medicine Nursing and Health Science, Monash University, Clayton, VIC, Australia.
  26. Department of Orthopaedics and Sports Medicine, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands.
  27. School of Health and Rehabilitation Sciences: Physiotherapy, The University of Queensland, Brisbane, QLD, Australia.

PMID: 34797533 DOI: 10.1007/s40279-021-01588-6

Abstract

BACKGROUND: Nine core domains for tendinopathy have been identified. For Achilles tendinopathy there is large variation in outcome measures used, and how these fit into the core domains has not been investigated.

OBJECTIVE: To identify all available outcome measures outcome measures used to assess the clinical phenotype of Achilles tendinopathy in prospective studies and to map the outcomes measures into predefined health-related core domains.

DESIGN: Systematic review.

DATA SOURCES: Embase, MEDLINE (Ovid), Web of Science, CINAHL, The Cochrane Library, SPORTDiscus and Google Scholar.

ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Clinical diagnosis of Achilles tendinopathy, sample size ≥ ten participants, age ≥ 16 years, and the study design was a randomized or non-randomized clinical trial, observational cohort, single-arm intervention, or case series.

RESULTS: 9376 studies were initially screened and 307 studies were finally included, totaling 13,248 participants. There were 233 (177 core domain) different outcome measures identified across all domains. For each core domain outcome measures were identified, with a range between 8 and 35 unique outcome measures utilized for each domain. The proportion of studies that included outcomes for predefined core domains ranged from 4% for the psychological factors domain to 72% for the disability domain.

CONCLUSION: 233 unique outcome measures for Achilles tendinopathy were identified. Most frequently, outcome measures were used within the disability domain. Outcome measures assessing psychological factors were scarcely used. The next step in developing a core outcome set for Achilles tendinopathy is to engage patients, clinicians and researchers to reach consensus on key outcomes measures.

PROSPERO REGISTRATION: CRD42020156763.

© 2021. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

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