Display options
Cite
Mancini SJC, Balabanian K, Corre I, et al. Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies. Front Immunol. 2021;12:766275doi: 10.3389/fimmu.2021.766275.
Mancini, S. J. C., Balabanian, K., Corre, I., Gavard, J., Lazennec, G., Le Bousse-Kerdilès, M. C., Louache, F., Maguer-Satta, V., Mazure, N. M., Mechta-Grigoriou, F., Peyron, J. F., Trichet, V., & Herault, O. (2021). Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies. Frontiers in immunology, 12766275. https://doi.org/10.3389/fimmu.2021.766275
Mancini, Stéphane J C, et al. "Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies." Frontiers in immunology vol. 12 (2021): 766275. doi: https://doi.org/10.3389/fimmu.2021.766275
Mancini SJC, Balabanian K, Corre I, Gavard J, Lazennec G, Le Bousse-Kerdilès MC, Louache F, Maguer-Satta V, Mazure NM, Mechta-Grigoriou F, Peyron JF, Trichet V, Herault O. Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies. Front Immunol. 2021 Nov 10;12:766275. doi: 10.3389/fimmu.2021.766275. eCollection 2021. PMID: 34858421; PMCID: PMC8631445.
Copy Download .nbib Format: NLM
Share it on

Front Immunol. 2021 Nov 10;12:766275. doi: 10.3389/fimmu.2021.766275. eCollection 2021.

Deciphering Tumor Niches: Lessons From Solid and Hematological Malignancies.

Frontiers in immunology

Stéphane J C Mancini, Karl Balabanian, Isabelle Corre, Julie Gavard, Gwendal Lazennec, Marie-Caroline Le Bousse-Kerdilès, Fawzia Louache, Véronique Maguer-Satta, Nathalie M Mazure, Fatima Mechta-Grigoriou, Jean-François Peyron, Valérie Trichet, Olivier Herault

Affiliations

  1. Centre National de la Recherche scientifique (CNRS) GDR3697, Micronit "Microenvironment of Tumor Niches", Tours, France.
  2. INSERM UMR1236, Rennes 1 University, Etablissement Français du Sang Bretagne, Rennes, France.
  3. Cancéropole Grand-Ouest, NET network "Niches and Epigenetics of Tumors", Nantes, France.
  4. Saint-Louis Research Institute, University of Paris, EMiLy, INSERM U1160, Paris, France.
  5. The Organization for Partnerships in Leukemia (OPALE) Carnot Institute, The Organization for Partnerships in Leukemia, Paris, France.
  6. Center for Research in Cancerology and Immunology Nantes-Angers (CRCINA), Signaling in Oncogenesis Angiogenesis and Permeability (SOAP), INSERM UMR1232, Centre National de la Recherche scientifique (CNRS) ERL600, Université de Nantes, Nantes, France.
  7. Integrated Center for Oncology, St. Herblain, France.
  8. Centre National de la Recherche scientifique (CNRS) UMR9005, SYS2DIAG-ALCEDIAG, Montpellier, France.
  9. INSERM UMRS-MD1197, Paris-Saclay University, Paul-Brousse Hospital, Villejuif, France.
  10. Cancer Research Center of Lyon (CRCL), CNRS UMR5286, INSERM U1052, Lyon 1 university, Lean Bérard Center, Lyon, France.
  11. INSERM U1065, C3M, University of Côte d'Azur (UCA), Nice, France.
  12. Stress and Cancer Laboratory, Institut Curie, INSERM U830, Paris Sciences et Lettres (PSL) Research University, Team Babelized Ligue Nationale Contre le Cancer (LNCC), Paris, France.
  13. INSERM UMR1238 Phy-Os, Université de Nantes, Nantes, France.
  14. Centre National de la Recherche scientifique (CNRS) ERL7001 LNOx, EA7501, Tours University, Tours, France.
  15. Department of Biological Hematology, Tours University Hospital, Tours, France.

PMID: 34858421 PMCID: PMC8631445 DOI: 10.3389/fimmu.2021.766275

Abstract

Knowledge about the hematopoietic niche has evolved considerably in recent years, in particular through

Copyright © 2021 Mancini, Balabanian, Corre, Gavard, Lazennec, Le Bousse-Kerdilès, Louache, Maguer-Satta, Mazure, Mechta-Grigoriou, Peyron, Trichet and Herault.

Keywords: angiogenesis; cancer-associated fibroblasts (CAFs); cytokines and chemokines; endothelial plasticity; energy/oxidative metabolism; mesenchymal stem/stromal cells (MSCs); microenvironment; mitochondrial transfer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

  1. Cell Metab. 2019 Feb 5;29(2):399-416.e10 - PubMed
  2. Front Immunol. 2020 Nov 26;11:600127 - PubMed
  3. Nature. 2018 Feb 22;554(7693):544-548 - PubMed
  4. Nat Cancer. 2020 Jul;1(7):672-680 - PubMed
  5. Blood. 2013 Jan 10;121(2):360-8 - PubMed
  6. Nature. 2014 Oct 30;514(7524):628-32 - PubMed
  7. J Natl Cancer Inst. 2019 Sep 1;111(9):983-995 - PubMed
  8. Cancer Res. 2007 Nov 1;67(21):10123-8 - PubMed
  9. Nature. 1999 May 20;399(6733):271-5 - PubMed
  10. J Clin Invest. 2011 Aug;121(8):3206-19 - PubMed
  11. Semin Oncol. 2017 Jun;44(3):198-203 - PubMed
  12. Trends Mol Med. 2010 Mar;16(3):133-44 - PubMed
  13. Nature. 2016 Aug 25;536(7617):479-83 - PubMed
  14. J Pathol. 2019 May;248(1):51-65 - PubMed
  15. Tumour Biol. 2016 Oct;37(10):13961-13971 - PubMed
  16. Cell Rep. 2019 Nov 19;29(8):2307-2320.e6 - PubMed
  17. Front Oncol. 2013 Aug 15;3:211 - PubMed
  18. EMBO Mol Med. 2019 Aug;11(8):e9266 - PubMed
  19. Biochim Biophys Acta. 2016 Dec;1866(2):290-299 - PubMed
  20. Blood. 2016 Jul 14;128(2):253-64 - PubMed
  21. Stem Cell Res Ther. 2014 Apr 16;5(2):53 - PubMed
  22. Nat Commun. 2018 Dec 4;9(1):5150 - PubMed
  23. Nat Commun. 2018 Nov 30;9(1):5108 - PubMed
  24. Annu Rev Cell Dev Biol. 2016 Oct 6;32:649-675 - PubMed
  25. Cell Stem Cell. 2021 Apr 1;28(4):653-670.e11 - PubMed
  26. Blood. 2019 Oct 24;134(17):1415-1429 - PubMed
  27. Trends Cancer. 2017 Dec;3(12):828-839 - PubMed
  28. Oncogene. 2018 Aug;37(32):4343-4357 - PubMed
  29. Cancer Immunol Res. 2018 Dec;6(12):1472-1485 - PubMed
  30. Br J Haematol. 2009 Jul;146(2):150-7 - PubMed
  31. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20212-7 - PubMed
  32. Nature. 2019 May;569(7755):222-228 - PubMed
  33. PLoS One. 2012;7(2):e30563 - PubMed
  34. Cancer Discov. 2012 Sep;2(9):840-55 - PubMed
  35. J Gastroenterol. 2014 Jul;49(7):1111-20 - PubMed
  36. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5510-4 - PubMed
  37. Front Cell Dev Biol. 2019 Sep 13;7:189 - PubMed
  38. J Bone Miner Res. 2014 Dec;29(12):2688-96 - PubMed
  39. Nature. 2015 Oct 1;526(7571):126-30 - PubMed
  40. Cancer Cell. 2012 Apr 17;21(4):577-92 - PubMed
  41. Haematologica. 2021 Mar 01;106(3):865-870 - PubMed
  42. Biomech Model Mechanobiol. 2011 Dec;10(6):939-53 - PubMed
  43. Stem Cell Reports. 2017 Jun 6;8(6):1573-1586 - PubMed
  44. Sci Rep. 2015 Mar 13;5:9073 - PubMed
  45. Cell Stem Cell. 2019 Jan 3;24(1):41-53 - PubMed
  46. Cancer Cell. 2021 Apr 12;39(4):548-565.e6 - PubMed
  47. Cancer Cell. 2012 Mar 20;21(3):297-308 - PubMed
  48. Cell Death Dis. 2018 Sep 27;9(10):1011 - PubMed
  49. J Exp Med. 2017 Mar 6;214(3):579-596 - PubMed
  50. Am J Pathol. 2017 Aug;187(8):1879-1892 - PubMed
  51. Cell Stem Cell. 2014 Sep 4;15(3):365-375 - PubMed
  52. Cancer Res. 2020 Feb 1;80(3):484-498 - PubMed
  53. Cancer Discov. 2017 Jul;7(7):716-735 - PubMed
  54. Front Cell Dev Biol. 2020 Aug 14;8:747 - PubMed
  55. Cancer Metastasis Rev. 2006 Dec;25(4):621-33 - PubMed
  56. Nature. 2005 Sep 22;437(7058):497-504 - PubMed
  57. Blood. 1993 Mar 1;81(5):1205-13 - PubMed
  58. Immunity. 2021 May 11;54(5):859-874 - PubMed
  59. Oncotarget. 2015 Oct 6;6(30):29034-47 - PubMed
  60. Cancer Discov. 2021 Apr;11(4):933-959 - PubMed
  61. Leukemia. 2014 Oct;28(10):1978-1987 - PubMed
  62. Cell. 2018 Feb 8;172(4):841-856.e16 - PubMed
  63. Front Immunol. 2021 Apr 15;12:658535 - PubMed
  64. Cancer Discov. 2019 Aug;9(8):1102-1123 - PubMed
  65. Cancer Res. 2015 Jun 1;75(11):2222-31 - PubMed
  66. Cell. 2019 Aug 22;178(5):1088-1101.e15 - PubMed
  67. Blood. 2021 Jul 8;138(1):57-70 - PubMed
  68. J Biol Chem. 1995 Jan 20;270(3):1230-7 - PubMed
  69. Acta Biomater. 2021 Oct 1;133:114-125 - PubMed
  70. Nat Rev Cancer. 2005 Jan;5(1):21-8 - PubMed
  71. Cancer Cell. 2007 Jan;11(1):69-82 - PubMed
  72. J Leukoc Biol. 2018 Mar;103(3):457-464 - PubMed
  73. J Bone Oncol. 2015 Dec 12;5(1):5-14 - PubMed
  74. Front Cell Dev Biol. 2020 Nov 19;8:545126 - PubMed
  75. Front Oncol. 2016 Feb 26;6:41 - PubMed
  76. Int J Cancer. 2017 Mar 15;140(6):1331-1345 - PubMed
  77. Cell Cycle. 2010 Jun 15;9(12):2412-22 - PubMed
  78. Cancer Cell. 2018 Mar 12;33(3):463-479.e10 - PubMed
  79. Nat Commun. 2017 Feb 09;8:14361 - PubMed
  80. Cancer Cell. 2018 May 14;33(5):874-889.e7 - PubMed
  81. Sci Transl Med. 2020 Feb 26;12(532): - PubMed
  82. Cell Death Differ. 2017 Jul;24(7):1224-1238 - PubMed
  83. PLoS Biol. 2016 Sep 21;14(9):e1002562 - PubMed
  84. Cell Stem Cell. 2019 Oct 3;25(4):570-583.e7 - PubMed
  85. Cancer Metastasis Rev. 1989 Aug;8(2):98-101 - PubMed
  86. J Exp Med. 2012 May 7;209(5):895-901 - PubMed
  87. Proc Natl Acad Sci U S A. 1982 Jun;79(11):3608-12 - PubMed
  88. Int J Mol Sci. 2021 Jan 21;22(3): - PubMed
  89. Science. 2001 Apr 20;292(5516):464-8 - PubMed
  90. Mol Oncol. 2018 May;12(5):659-676 - PubMed
  91. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E992-E1001 - PubMed
  92. Haematologica. 2019 Jan;104(1):70-81 - PubMed
  93. Leukemia. 2019 Apr;33(4):918-930 - PubMed
  94. Int J Mol Sci. 2020 Nov 14;21(22): - PubMed
  95. Stem Cells. 2008 Jun;26(6):1387-94 - PubMed
  96. Brain. 2017 Nov 1;140(11):2939-2954 - PubMed
  97. J Clin Invest. 2008 Dec;118(12):3930-42 - PubMed
  98. Fibrogenesis Tissue Repair. 2012 Jun 06;5(Suppl 1):S20 - PubMed
  99. Cell Rep. 2019 Mar 19;26(12):3257-3271.e8 - PubMed
  100. J Orthop Res. 1991 Sep;9(5):641-50 - PubMed
  101. Nat Rev Cancer. 2020 May;20(5):285-298 - PubMed
  102. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1283-8 - PubMed
  103. Nature. 2007 Oct 4;449(7162):557-63 - PubMed
  104. Stem Cell Reports. 2015 Feb 10;4(2):239-54 - PubMed
  105. Nat Commun. 2018 Mar 13;9(1):1056 - PubMed
  106. Cancer Discov. 2020 Feb;10(2):232-253 - PubMed
  107. Nature. 2014 Mar 20;507(7492):323-328 - PubMed
  108. Cancer Metastasis Rev. 2006 Dec;25(4):601-9 - PubMed
  109. Genom Data. 2015 Apr 29;5:1-2 - PubMed
  110. Cytotherapy. 2006;8(4):315-7 - PubMed
  111. Oncogene. 2019 Jun;38(25):4887-4901 - PubMed
  112. Nat Rev Immunol. 2020 Aug;20(8):483-497 - PubMed
  113. Cancers (Basel). 2020 Jan 24;12(2): - PubMed
  114. PLoS One. 2015 Mar 05;10(3):e0119655 - PubMed
  115. EMBO Rep. 2011 May;12(5):470-6 - PubMed
  116. Blood. 2009 Jun 4;113(23):5878-86 - PubMed
  117. J Exp Med. 2013 Jul 1;210(7):1351-67 - PubMed
  118. Cell Metab. 2015 Oct 6;22(4):590-605 - PubMed
  119. J Cell Physiol. 1977 Jun;91(3):335-44 - PubMed
  120. Stem Cell Res Ther. 2021 Jan 7;12(1):25 - PubMed
  121. Nat Rev Cancer. 2020 Mar;20(3):174-186 - PubMed
  122. Oncotarget. 2017 Mar 21;8(12):19780-19794 - PubMed
  123. Int J Mol Sci. 2018 Mar 01;19(3): - PubMed
  124. Cell. 2019 Jun 13;177(7):1915-1932.e16 - PubMed
  125. Cell Metab. 2015 Jan 6;21(1):81-94 - PubMed
  126. Blood. 2017 Oct 5;130(14):1649-1660 - PubMed
  127. Stem Cell Res Ther. 2018 Oct 25;9(1):271 - PubMed
  128. Front Endocrinol (Lausanne). 2017 Nov 03;8:296 - PubMed
  129. Am J Pathol. 2000 Jul;157(1):15-9 - PubMed
  130. Nat Rev Cancer. 2021 Jun;21(6):345-359 - PubMed
  131. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9066-E9075 - PubMed
  132. Thromb Haemost. 2018 Sep;118(9):1586-1599 - PubMed
  133. Genes Dev. 2012 Sep 1;26(17):1926-44 - PubMed
  134. Blood Rev. 2020 Jul;42:100715 - PubMed
  135. Nat Rev Immunol. 2017 Sep;17(9):573-590 - PubMed
  136. Blood. 2013 Nov 28;122(23):3767-77 - PubMed
  137. Front Oncol. 2021 Jan 08;10:606540 - PubMed
  138. Haematologica. 2020 Jan 30;106(1):111-122 - PubMed
  139. Endocr Relat Cancer. 2009 Sep;16(3):663-73 - PubMed
  140. Cell Stem Cell. 2019 May 2;24(5):769-784.e6 - PubMed
  141. Nat Rev Cancer. 2007 Oct;7(10):733-6 - PubMed
  142. Science. 2017 Dec 1;358(6367): - PubMed
  143. Nature. 2021 May;593(7860):575-579 - PubMed
  144. Cells. 2019 Feb 13;8(2): - PubMed
  145. J Pathol. 2020 Apr;250(5):555-572 - PubMed
  146. Science. 2001 Apr 20;292(5516):468-72 - PubMed
  147. Genes Dev. 2012 May 1;26(9):877-90 - PubMed
  148. Nature. 2016 Apr 21;532(7599):323-8 - PubMed
  149. Dev Cell. 2021 Jul 12;56(13):1848-1860 - PubMed
  150. Cell Stem Cell. 2018 Jan 4;22(1):64-77.e6 - PubMed
  151. Immunity. 2010 Sep 24;33(3):387-99 - PubMed
  152. Cancer Cell. 2017 Sep 11;32(3):324-341.e6 - PubMed
  153. Blood. 2011 Mar 3;117(9):2700-7 - PubMed
  154. Cancers (Basel). 2021 Jan 22;13(3): - PubMed
  155. Cold Spring Harb Perspect Med. 2018 Jun 1;8(6): - PubMed
  156. Cancer Res. 2015 Nov 15;75(22):4753-65 - PubMed
  157. Oncogene. 2016 May 19;35(20):2615-23 - PubMed
  158. Nat Med. 2012 Apr 15;18(5):759-65 - PubMed
  159. Mediators Inflamm. 2015;2015:102476 - PubMed
  160. Immunity. 2019 Aug 20;51(2):411-412 - PubMed
  161. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16062-7 - PubMed
  162. Nat Commun. 2020 Apr 27;11(1):2042 - PubMed
  163. Cancer Discov. 2020 Sep;10(9):1330-1351 - PubMed
  164. Blood. 2000 Sep 15;96(6):2240-5 - PubMed
  165. Nature. 2021 May;593(7860):586-590 - PubMed
  166. J Extracell Vesicles. 2017 Aug 8;6(1):1359479 - PubMed
  167. Cancers (Basel). 2020 Jul 27;12(8): - PubMed
  168. Nature. 2001 Mar 1;410(6824):50-6 - PubMed
  169. Breast Cancer Res. 2020 Jul 14;22(1):76 - PubMed
  170. Stem Cell Res Ther. 2020 Aug 14;11(1):357 - PubMed
  171. Eur J Haematol. 2016 Sep;97(3):245-52 - PubMed
  172. Cell Metab. 2020 Nov 3;32(5):829-843.e9 - PubMed
  173. Oncogene. 2008 Apr 17;27(18):2542-51 - PubMed
  174. Stem Cells Dev. 2017 May 15;26(10):709-722 - PubMed
  175. Nat Rev Clin Oncol. 2021 Aug;18(8):488-505 - PubMed
  176. Nature. 2012 Jan 25;481(7382):457-62 - PubMed
  177. Br J Haematol. 2021 May;193(3):659-668 - PubMed
  178. Elife. 2017 Feb 15;6: - PubMed
  179. Nat Commun. 2020 Jan 21;11(1):404 - PubMed
  180. Essays Biochem. 2007;43:165-78 - PubMed
  181. Blood. 2008 Oct 15;112(8):3026-35 - PubMed
  182. Cell Stem Cell. 2019 Dec 5;25(6):768-783.e6 - PubMed
  183. EMBO Rep. 2020 Feb 5;21(2):e48052 - PubMed
  184. Cell Death Differ. 2015 Jul;22(7):1181-91 - PubMed
  185. Sci Rep. 2021 Feb 18;11(1):4219 - PubMed
  186. Cell Metab. 2019 Jan 8;29(1):156-173.e10 - PubMed
  187. Mediators Inflamm. 2015;2015:415024 - PubMed
  188. Leukemia. 2016 Mar;30(3):683-91 - PubMed
  189. Cell Rep. 2019 Jul 9;28(2):302-311.e5 - PubMed
  190. Science. 1956 Feb 24;123(3191):309-14 - PubMed
  191. Cancer Cell. 2013 Mar 18;23(3):287-301 - PubMed
  192. Int J Mol Sci. 2018 Aug 10;19(8): - PubMed
  193. Blood. 2019 May 16;133(20):2159-2167 - PubMed
  194. Blood. 2017 Feb 16;129(7):811-822 - PubMed

Publication Types