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Hum Immunol. 2021 Nov 18; doi: 10.1016/j.humimm.2021.11.003. Epub 2021 Nov 18.

T cell subpopulations and cytokine levels in hemodialysis patients.

Human immunology

Katarzyna A Lisowska, Hanna Storoniak, Alicja Dębska-Ślizień

Affiliations

  1. Department of Pathophysiology, Faculty of Medicine, Medical University of Gda?sk, Gda?sk, Poland. Electronic address: [email protected].
  2. Department of Nephrology, Transplantology and Internal Medicine, Faculty of Medicine, Medical University of Gda?sk, Gda?sk, Poland.

PMID: 34802797 DOI: 10.1016/j.humimm.2021.11.003

Abstract

HD patients have impaired adaptive immune responses, which might depend on the primary cause of chronic kidney disease (CKD). We analyzed percentages of T cells subpopulations with the expression of CD69, CD25, CD95, and HLA-DR antigens in HD patients to determine the status of T cell activation. Also, we determined serum levels of cytokines: IL12p70, TNF, IL-10, IL-6, IL-1β, IL-8. HD patients had increased percentages of CD4

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Keywords: Activation antigens; Cytokines; End-stage renal disease; Hemodialysis; T cells

Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this pa

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