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Vaccines (Basel). 2021 Nov 17;9(11). doi: 10.3390/vaccines9111337.

Production and Characterization of Nucleocapsid and RBD Cocktail Antigens of SARS-CoV-2 in .

Vaccines

Tarlan Mamedov, Damla Yuksel, Merve Ilgın, Irem Gürbüzaslan, Burcu Gulec, Gulshan Mammadova, Aykut Ozdarendeli, Hazel Yetiskin, Busra Kaplan, Shaikh Terkis Islam Pavel, Muhammet Ali Uygut, Gulnara Hasanova

Affiliations

  1. Department of Agricultural Biotechnology, Akdeniz University, Antalya 07058, Turkey.
  2. Department of Microbiology, Medical Faculty, Erciyes University, Kayseri 38280, Turkey.
  3. Vaccine Research, Development and Application Center, Erciyes University, Kayseri 38280, Turkey.

PMID: 34835268 PMCID: PMC8621474 DOI: 10.3390/vaccines9111337

Abstract

The COVID-19 pandemic has put global public health at high risk, rapidly spreading around the world. Although several COVID-19 vaccines are available for mass immunization, the world still urgently needs highly effective, reliable, cost-effective, and safe SARS-CoV-2 coronavirus vaccines, as well as antiviral and therapeutic drugs, to control the COVID-19 pandemic given the emerging variant strains of the virus. Recently, we successfully produced receptor-binding domain (RBD) variants in the

Keywords: COVID-19; RBD of SARS-CoV-2; SARS-CoV-2; nucleocapsid protein; plant; transient expression system

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