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Cai S, Kumar R, Singh BR. Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins. Microorganisms. 2021;9(11)doi: 10.3390/microorganisms9112206.
Cai, S., Kumar, R., & Singh, B. R. (2021). Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins. Microorganisms, 9(11), . https://doi.org/10.3390/microorganisms9112206
Cai, Shuowei, et al. "Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins." Microorganisms vol. 9,11 (2021). doi: https://doi.org/10.3390/microorganisms9112206
Cai S, Kumar R, Singh BR. Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins. Microorganisms. 2021 Oct 23;9(11). doi: 10.3390/microorganisms9112206. PMID: 34835332; PMCID: PMC8618262.
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Microorganisms. 2021 Oct 23;9(11). doi: 10.3390/microorganisms9112206.

Clostridial Neurotoxins: Structure, Function and Implications to Other Bacterial Toxins.

Microorganisms

Shuowei Cai, Raj Kumar, Bal Ram Singh

Affiliations

  1. Department of Chemistry and Biochemistry, University of Massachusetts Dartmouth, Dartmouth, MA 02747, USA.
  2. Botulinum Research Center, Institute of Advanced Sciences, Dartmouth, MA 02747, USA.

PMID: 34835332 PMCID: PMC8618262 DOI: 10.3390/microorganisms9112206

Abstract

Gram-positive bacteria are ancient organisms. Many bacteria, including Gram-positive bacteria, produce toxins to manipulate the host, leading to various diseases. While the targets of Gram-positive bacterial toxins are diverse, many of those toxins use a similar mechanism to invade host cells and exert their functions. Clostridial neurotoxins produced by

Keywords: Gram-positive bacterial toxins; anthrax toxin; botulinum neurotoxin; clostridial neurotoxin; diphtheria toxin; molten globule; pore-forming toxins; proteolytic activation; tetanus neurotoxin

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