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Farhat SCL, Ejnisman C, Alves AGF, et al. Air pollution influence on serum inflammatory interleukins: A prospective study in childhood-onset systemic lupus erythematous patients. Lupus. 2021;9612033211061479doi: 10.1177/09612033211061479.
Farhat, S. C. L., Ejnisman, C., Alves, A. G. F., Goulart, M. F. G., Lichtenfels, A. J. F. C., Braga, A. L. F., Pereira, L. A. A., Maluf Elias, A., & Silva, C. A. (2021). Air pollution influence on serum inflammatory interleukins: A prospective study in childhood-onset systemic lupus erythematous patients. Lupus, 9612033211061479. https://doi.org/10.1177/09612033211061479
Farhat, Sylvia Costa Lima, et al. "Air pollution influence on serum inflammatory interleukins: A prospective study in childhood-onset systemic lupus erythematous patients." Lupus vol. (2021): 9612033211061479. doi: https://doi.org/10.1177/09612033211061479
Farhat SCL, Ejnisman C, Alves AGF, Goulart MFG, Lichtenfels AJFC, Braga ALF, Pereira LAA, Maluf Elias A, Silva CA. Air pollution influence on serum inflammatory interleukins: A prospective study in childhood-onset systemic lupus erythematous patients. Lupus. 2021 Dec 09;9612033211061479. doi: 10.1177/09612033211061479. Epub 2021 Dec 09. PMID: 34879788.
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Lupus. 2021 Dec 09;9612033211061479. doi: 10.1177/09612033211061479. Epub 2021 Dec 09.

Air pollution influence on serum inflammatory interleukins: A prospective study in childhood-onset systemic lupus erythematous patients.

Lupus

Sylvia Costa Lima Farhat, Carolina Ejnisman, Andressa Guariento Ferreira Alves, Maria Fernanda Giacomin Goulart, Ana Julia de Faria Coimbra Lichtenfels, Alfésio Luis Ferreira Braga, Luiz Alberto Amador Pereira, Adriana Maluf Elias, Clovis A Silva

Affiliations

  1. Environmental Epidemiology Study Group, Laboratory of Experimental Air Pollution, 37884Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
  2. Laboratory of Experimental Air Pollution, LIM05, Faculdade de Medicina FMUSP, 37884Universidade de Sao Paulo, São Paulo, Brazil.
  3. Pediatric Department Hospital das Clinicas HCFMUSP, Faculdade de Medicina, 37884Universidade de Sao Paulo, São Paulo, Brazil.
  4. 428062Universidade de Santo Amaro, Sao Paulo, Brazil.
  5. Environmental Exposure and Risk Assessment Group, Collective Health Post-graduation Program, 67888Universidade Catolica de Santos, Santos, Brazil.
  6. Pediatric Rheumatology Unit, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, 28133Universidade de Sao Paulo, São Paulo, Brazil.
  7. Division of Rheumatology, Faculdade de Medicina FMUSP, 37884Universidade de Sao Paulo, São Paulo, Brazil.

PMID: 34879788 DOI: 10.1177/09612033211061479

Abstract

OBJECTIVE: To assess the effect of individual exposure, in real-time, to traffic-related pollutants on serum interleukin levels of childhood-onset lupus erythematous systemic (c-SLE) patients.

METHODS: A longitudinal and observational design was conducted in 12 repeated measures of serum samples and clinical evaluations (totaling 108 measurements) of c-SLE patients over 30 consecutive months. Real-time, individual exposure to fine particles (PM

RESULTS: An interquartile range (IQR) increase in PM

CONCLUSION: Real-time exposure to PM

Keywords: Childhood-systemic lupus erythematosus; air pollution; inhalable fine particles; real-time exposure; serum cytokines; traffic-related-pollution

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