J Low Genit Tract Dis. 2021 Nov 25; doi: 10.1097/LGT.0000000000000641. Epub 2021 Nov 25.
Mixed Vaginitis Due to Bacterial Vaginosis and Candidiasis.
Journal of lower genital tract disease
Dana Benyas, Jack D Sobel
Affiliations
Affiliations
- Department of Internal Medicine, Wayne State University School of Medicine Detroit, MI.
PMID: 34840242
DOI: 10.1097/LGT.0000000000000641
Abstract
OBJECTIVE: The aim of the study was to review recent clinic cases with mixed vaginitis due to bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC) with reference to demographics, clinical presentation, diagnosis, and treatment.
MATERIALS AND METHODS: This is a retrospective chart review of patients defined with mixed vaginitis due to BV and VVC in academic vaginitis clinic over 3 years (2018-2021).
RESULTS: Thirty-eight women, mean age 32.6 years, met mixed vaginitis definition criteria. Diagnosis was invariably suspected clinically and rapidly confirmed using standard point of care diagnostic tests. Most patients (>90%) had a history of long-standing recurrent vaginitis both BV and VVC. Condom use was infrequent at 30% and 100% of yeast isolates were Candida albicans. Dual antimicrobial therapy achieved short term therapeutic success in 66.7% with failure in part due to fluconazole resistant C. albicans strains.
CONCLUSIONS: Mixed vaginitis is not uncommon and serves as a significant therapeutic challenge requiring initial dual antimicrobial therapy and additional consideration for long-term antimicrobial therapy.
Copyright © 2021 by the American Society for Colposcopy and Cervical Pathology.
Conflict of interest statement
The authors have declared they have no conflicts of interest.
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