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Licari A, Manti S, Leonardi S, et al. Biologic drugs in chronic spontaneous urticaria. Acta Biomed. 2021;92:e2021527doi: 10.23750/abm.v92iS7.12415.
Licari, A., Manti, S., Leonardi, S., Minasi, D., Caffarelli, C., Cardinale, F., Miraglia Del Giudice, M., Calvani, M., Ciprandi, G., & Marseglia, G. L. (2021). Biologic drugs in chronic spontaneous urticaria. Acta bio-medica : Atenei Parmensis, 92e2021527. https://doi.org/10.23750/abm.v92iS7.12415
Licari, Amelia, et al. "Biologic drugs in chronic spontaneous urticaria." Acta bio-medica : Atenei Parmensis vol. 92 (2021): e2021527. doi: https://doi.org/10.23750/abm.v92iS7.12415
Licari A, Manti S, Leonardi S, Minasi D, Caffarelli C, Cardinale F, Miraglia Del Giudice M, Calvani M, Ciprandi G, Marseglia GL. Biologic drugs in chronic spontaneous urticaria. Acta Biomed. 2021 Nov 29;92:e2021527. doi: 10.23750/abm.v92iS7.12415. PMID: 34842589.
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Acta Biomed. 2021 Nov 29;92:e2021527. doi: 10.23750/abm.v92iS7.12415.

Biologic drugs in chronic spontaneous urticaria.

Acta bio-medica : Atenei Parmensis

Amelia Licari, Sara Manti, Salvatore Leonardi, Domenico Minasi, Carlo Caffarelli, Fabio Cardinale, Michele Miraglia Del Giudice, Mauro Calvani, Giorgio Ciprandi, Gian Luigi Marseglia

Affiliations

  1. 1Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. [email protected].
  2. 1UOC Broncopneumologia Pediatrica e Fibrosi Cistica, AOUP "Vittorio-Emanuele", San Marco Hospital, Università di Catania, Catania, Italy. [email protected].
  3. 3Department of Clinical and Experimental Medicine, Pediatric Respiratory Unit, San Marco Hospital, University of Catania, Catania, Italy. [email protected].
  4. Pediatric Unit Great Metropolitan Hospital Reggio Calabria, Reggio Calabria, Italy. [email protected].
  5. Pediatric Clinic, Department of Medicine and Surgery, Unversity of Parma, Parma, Italy. [email protected].
  6. Department of Pediatrics, Giovanni XXIII Pediatric Hospital, University of Bari, Bari, Italy. [email protected].
  7. Department of Woman, Child and Specialized Surgery, University of Campania "Luigi Vanvitelli. [email protected].
  8. UOC di Pediatria. Azienda ospedaliera S. Camillo Forlanini, Rome, Italy. [email protected].
  9. Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy. [email protected].
  10. Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy. [email protected].

PMID: 34842589 DOI: 10.23750/abm.v92iS7.12415

Abstract

Chronic spontaneous urticaria (CSU) is a condition defined by the presence of recurrent urticaria, angioedema, or both, which persist for more than six weeks in duration and occurs in the absence of an identifiable trigger. Both children and adults can develop CSU, although it is more common in adults and in women than in men, with a peak occurrence in the third to fifth decades of life. It imposes a significant burden on patients, families and healthcare systems. The goal of therapy in patients with CSU is to achieve a level of symptom control and improvement in quality of life that is acceptable to the patient, while minimizing therapy-related side effects. The recent introduction of biologic drugs has changed the management of the disease. This work aims to provide a narrative review of the current state of biological therapy and the promising drugs under development for CSU.

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