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J Clin Med. 2021 Nov 29;10(23). doi: 10.3390/jcm10235619.

Background Factors Affecting Visual Acuity at Initial Visit in Eyes with Central Retinal Vein Occlusion: Multicenter Study in Japan.

Journal of clinical medicine

Mineo Kondo, Hidetaka Noma, Masahiko Shimura, Masahiko Sugimoto, Yoshitsugu Matsui, Kumiko Kato, Yoshitsugu Saishin, Masahito Ohji, Hiroto Ishikawa, Fumi Gomi, Kensaku Iwata, Shigeo Yoshida, Sentaro Kusuhara, Hiromasa Hirai, Nahoko Ogata, Takao Hirano, Toshinori Murata, Kotaro Tsuboi, Motohiro Kamei, Takamasa Kinoshita, Soichiro Kuwayama, Yoshio Hirano, Manami Ohta, Kazuhiro Kimura, Kei Takayama, Masaru Takeuchi, Yoshihiro Takamura, Fumiki Okamoto, Yoshinori Mitamura, Hiroto Terasaki, Taiji Sakamoto, On Behalf Of Japan Clinical Retina Study J-Crest Group

Affiliations

  1. Department of Ophthalmology, Mie University Graduate School of Medicine, Tsu 514-8507, Japan.
  2. Department of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Hachioji 193-0998, Japan.
  3. Department of Ophthalmology, Shiga University of Medical Science, Otsu 520-2192, Japan.
  4. Department of Ophthalmology, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.
  5. Department of Ophthalmology, Kurume University School of Medicine, Kurume 830-0011, Japan.
  6. Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
  7. Department of Ophthalmology, Nara Medical University, Kashihara 634-8521, Japan.
  8. Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto 390-8621, Japan.
  9. Department of Ophthalmology, Aichi Medical University, Nagakute 480-1195, Japan.
  10. Department of Ophthalmology, Sapporo City General Hospital, Sapporo 060-8604, Japan.
  11. Department of Ophthalmology & Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya 467-8601, Japan.
  12. Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube 755-8505, Japan.
  13. Department of Ophthalmology, National Defense Medical College, Tokorozawa 359-8513, Japan.
  14. Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Yoshida 910-1193, Japan.
  15. Department of Ophthalmology, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
  16. Department of Ophthalmology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima 770-8503, Japan.
  17. Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima 890-8544, Japan.

PMID: 34884321 DOI: 10.3390/jcm10235619

Abstract

PURPOSE: To determine the baseline characteristics of patients with central retinal vein occlusion (CRVO) that were significantly associated with the best-corrected visual acuity (BCVA) at the initial examination.

METHODS: This was a retrospective multicenter study using the medical records registered in 17 ophthalmological institutions in Japan. Patients with untreated CRVO (≥20-years-of-age) who were initially examined between January 2013 and December 2017 were studied. The patients' baseline factors that were significantly associated with the BCVA at the initial examination were determined by univariate and multivariate linear regression analyses.

RESULTS: Data from 517 eyes of 517 patients were analyzed. Univariate analyses showed that an older age (

CONCLUSIONS: The results indicate that an older age, a known strong factor, and the right eye were significantly associated with poorer BCVA at the initial visit to the hospital. These results suggest that functional and/or anatomical differences between the right and left eyes may be involved in these results.

Keywords: central retinal vein occlusion; multicenter study; visual acuity

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