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Int J Mol Sci. 2021 Dec 02;22(23). doi: 10.3390/ijms222313055.

Calmodulin-Connexin Partnership in Gap Junction Channel Regulation-Calmodulin-Cork Gating Model.

International journal of molecular sciences

Camillo Peracchia, Lillian Mae Leverone Peracchia

Affiliations

  1. Department of Pharmacology and Physiology, School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA.

PMID: 34884859 DOI: 10.3390/ijms222313055

Abstract

In the past four decades numerous findings have indicated that gap junction channel gating is mediated by intracellular calcium concentrations ([Ca

Keywords: calcium; calmodulin; cell communication; cell coupling; cell uncoupling; cell-to-cell channels; channel gating; connexins; gap junctions; innexins

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