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Cancers (Basel). 2021 Nov 23;13(23). doi: 10.3390/cancers13235893.

Delirium in Palliative Care.

Cancers

Patricia Bramati, Eduardo Bruera

Affiliations

  1. Department of Palliative Care, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1414, Houston, TX 77030, USA.

PMID: 34885002 DOI: 10.3390/cancers13235893

Abstract

Delirium, a widespread neuropsychiatric disorder in patients with terminal diseases, is associated with increased morbidity and mortality, profoundly impacting patients, their families, and caregivers. Although frequently missed, the effective recognition of delirium demands attention and commitment. Reversibility is frequently not achievable. Non-pharmacological and pharmacological interventions are commonly used but largely unproven. Palliative sedation, although controversial, should be considered for refractory delirium. Psychological assistance should be available to patients and their families at all times.

Keywords: antipsychotics; benzodiazepines; delirium; haloperidol; palliative; sedation

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