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Abrami M, Maschio M, Conese M, et al. Combined use of rheology and portable low-field NMR in cystic fibrosis patients. Respir Med. 2021;189:106623doi: 10.1016/j.rmed.2021.106623.
Abrami, M., Maschio, M., Conese, M., Confalonieri, M., Gerin, F., Dapas, B., Farra, R., Adrover, A., Torelli, L., Ruaro, B., Grassi, G., & Grassi, M. (2021). Combined use of rheology and portable low-field NMR in cystic fibrosis patients. Respiratory medicine, 189106623. https://doi.org/10.1016/j.rmed.2021.106623
Abrami, Michela, et al. "Combined use of rheology and portable low-field NMR in cystic fibrosis patients." Respiratory medicine vol. 189 (2021): 106623. doi: https://doi.org/10.1016/j.rmed.2021.106623
Abrami M, Maschio M, Conese M, Confalonieri M, Gerin F, Dapas B, Farra R, Adrover A, Torelli L, Ruaro B, Grassi G, Grassi M. Combined use of rheology and portable low-field NMR in cystic fibrosis patients. Respir Med. 2021 Nov-Dec;189:106623. doi: 10.1016/j.rmed.2021.106623. Epub 2021 Sep 25. PMID: 34624628.
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Respir Med. 2021 Nov-Dec;189:106623. doi: 10.1016/j.rmed.2021.106623. Epub 2021 Sep 25.

Combined use of rheology and portable low-field NMR in cystic fibrosis patients.

Respiratory medicine

Michela Abrami, Massimo Maschio, Massimo Conese, Marco Confalonieri, Fabio Gerin, Barbara Dapas, Rossella Farra, Alessandra Adrover, Lucio Torelli, Barbara Ruaro, Gabriele Grassi, Mario Grassi

Affiliations

  1. Department of Engineering and Architecture, University of Trieste, Via Valerio 6/A, I-34127, Trieste, Italy.
  2. Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Via Dell'Istria, 65, I-34137, Trieste, Italy.
  3. Department of Medical and Surgical Sciences, Foggia University, Ospedali Riuniti, Via L. Pinto, 1, I-71122, Foggia, Italy.
  4. Cattinara University Hospital, Pulmonology Department, Strada di Fiume 447, I-34149, Trieste, Italy.
  5. Department of Life Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149, Trieste, Italy.
  6. Clinical Department of Medical, Surgical and Health Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149, Trieste, Italy.
  7. Department of Chemical Engineering, Materials and Environment, Sapienza University of Roma, Via Eudossiana 18, I-00184, Rome, Italy.
  8. Department of Life Sciences, Cattinara University Hospital, Trieste University, Strada di Fiume 447, I-34149, Trieste, Italy. Electronic address: [email protected].

PMID: 34624628 DOI: 10.1016/j.rmed.2021.106623

Abstract

BACKGROUND: As most cystic fibrosis (CF) patients progress to respiratory failure, lung functionality assessment is pivotal. We previously developed a test that indirectly monitors airways (inflammation/functional test) by measuring the spin-spin relaxation time (T

METHODS: Sputum samples from 25 consenting CF subjects were analyzed by rheology tests (elastic modulus G and zero shear viscosity η

RESULTS: There was an inverse correlation between G and η

CONCLUSIONS: We demonstrated a correlation between T

Copyright © 2021 Elsevier Ltd. All rights reserved.

Keywords: Cystic fibrosis; Low field NMR; Rheology; Sputum

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