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Ågren J, Segar JL, Söderström F, et al. Fluid management considerations in extremely preterm infants born at 22-24 weeks of gestation. Semin Perinatol. 2021;151541doi: 10.1016/j.semperi.2021.151541.
Ågren, J., Segar, J. L., Söderström, F., & Bell, E. F. (2021). Fluid management considerations in extremely preterm infants born at 22-24 weeks of gestation. Seminars in perinatology, 151541. https://doi.org/10.1016/j.semperi.2021.151541
Ågren, Johan, et al. "Fluid management considerations in extremely preterm infants born at 22-24 weeks of gestation." Seminars in perinatology vol. (2021): 151541. doi: https://doi.org/10.1016/j.semperi.2021.151541
Ågren J, Segar JL, Söderström F, Bell EF. Fluid management considerations in extremely preterm infants born at 22-24 weeks of gestation. Semin Perinatol. 2021 Nov 10;151541. doi: 10.1016/j.semperi.2021.151541. Epub 2021 Nov 10. PMID: 34848064.
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Semin Perinatol. 2021 Nov 10;151541. doi: 10.1016/j.semperi.2021.151541. Epub 2021 Nov 10.

Fluid management considerations in extremely preterm infants born at 22-24 weeks of gestation.

Seminars in perinatology

Johan Ågren, Jeffrey L Segar, Fanny Söderström, Edward F Bell

Affiliations

  1. Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. Electronic address: [email protected].
  2. Deparment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
  3. Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
  4. Department of Pediatrics, University of Iowa, Iowa City, IA, USA.

PMID: 34848064 DOI: 10.1016/j.semperi.2021.151541

Abstract

Emerging data regarding the encouraging outcomes of extremely preterm infants from centers taking active approaches to the care of these infants have prompted dialogue regarding optimal medical management. Among the multitude of decisions providers make in caring for extremely premature infants is the prescribing of parenteral fluids. Surprisingly, there are limited data to guide evidenced-based approaches to fluid and electrolyte management in this population. Immaturity of renal function and skin barriers contribute to the impaired capacity of the preterm infant to maintain salt and water homeostasis. This perspective paper highlights developmental physiological properties of the kidney and skin, which the provider needs to understand to provide parenteral fluid therapy. Additionally, we provide recommendations for initial fluid and electrolyte management of the preterm infant based on novel data as well as the published literature.

Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.

Keywords: Electrolyte; Hyperosmolarity; Insensible water loss; Prematurity; Sodium; Transepidermal

Conflict of interest statement

Declaration of Competing Interest None

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