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Gerontology. 2021 Oct 18;1-8. doi: 10.1159/000518864. Epub 2021 Oct 18.

Self-Rated Health and Frailty in Older Adults from the Population-Based Three-City Bordeaux Cohort.

Gerontology

Sophie Pilleron, Mélanie Le Goff, Soufiane Ajana, Catherine Helmer, Karine Pérès, Jean-François Dartigues, Maturin Tabue-Teguo, Catherine Féart

Affiliations

  1. Univ. Bordeaux, Inserm, BPH, UMR 1219, Bordeaux, France.
  2. CHU de Guadeloupe, Université des Antilles, Pointe-à-Pitre, France.
  3. Nuffield Department of Population Health, University of Oxford, Big Data Institute, Oxford, United Kingdom.
  4. CIC-EC 1401, INSERM, Bordeaux University, CHU Bordeaux, Bordeaux, France.

PMID: 34818256 DOI: 10.1159/000518864

Abstract

INTRODUCTION: This study aimed to investigate whether self-rated health (SRH) predict frailty and its components among community dwellers aged 75 years and older.

METHODS: We ran a cross-sectional and prospective analysis from 643 and 379 participants of the Bordeaux Center (France) of the Three-City Study, respectively. We assessed SRH using a single question with 5 response options. We defined frailty as having at least 3 out of the following 5 criteria: weight loss, exhaustion, slowness, weakness, and low energy expenditure. We used multivariate logistic regression and Cox proportional hazard models.

RESULTS: At baseline, poor SRH was significantly associated with frailty (odds ratio = 5.2; 95% confidence interval [CI]: 2.9-9.5) and its components except for weakness. In the prospective analysis on nonfrail participants, poor SRH was associated with the 4-year risk of slowness (hazard ratio [HR] = 1.7; 95% CI: 1.1-2.6) but not with that of frailty (HR = 1.6; 95% CI: 0.9-2.9) or the other components.

CONCLUSIONS: In a French cohort of community dwellers aged 75 years or older, poorer SRH was associated with concomitant frailty and 70% higher risk of slowness over 4 years.

© 2021 S. Karger AG, Basel.

Keywords: Cohort study; Cross-sectional study; Frailty; Observational study; Self-rated health

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