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Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:2330-2334. doi: 10.1109/EMBC46164.2021.9630163.

A Non-invasive Radial Arterial Compliance Measuring Method using Bio-Impedance.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

Xiaochen Tang, Matija Jankovic, Roozbeh Jafari

PMID: 34890323 DOI: 10.1109/EMBC46164.2021.9630163

Abstract

Arterial compliance is one of the essential indicators of certain types of cardiovascular disease, with both systematic and local compliance exhibiting significance. Radial arterial compliance (RAC) has been regarded as an important type of local compliance in several long-term pathophysiological studies. Bio-Impedance (Bio-Z) is a non-invasive signal which can be used to unobtrusively monitor blood volume changes, captured using wearable sensors. In this paper, a compliance monitoring technique based on Bio-Z is proposed for long-term RAC measurements. Both the distensibility-blood pressure (BP) relation and compliance-mean artery pressure relation are analyzed to observe interparticipant compliance variations from four healthy participants, by controlling the blood flow in a way similar to the oscillometric method for BP measurement. A Bio-Z based compliance index (DBZI) is proposed that can be leveraged for continuous and unobtrusive sensing paradigms. A consecutive seven-day experiment shows that the mean and standard deviation values of the difference between the median value of the Bio-Z based beat-by-beat calculated compliance and DBZI are 0.17 and 0.20 mOhm/mmHg, respectively. This demonstrates the consistency and repeatability of the measurements. The results show that DBZI can track the Bio-Z based compliance with an error of 9.72% and 11.67%, compared to a gold standard, in terms of mean and standard deviation, respectively.

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