Display options
Cite
Campos-Perez W, Perez-Robles M, Rodriguez-Echevarria R, et al. High dietary ω-6:ω-3 PUFA ratio and simple carbohydrates as a potential risk factors for gallstone disease: A cross-sectional study. Clin Res Hepatol Gastroenterol. 2021;101802doi: 10.1016/j.clinre.2021.101802.
Campos-Perez, W., Perez-Robles, M., Rodriguez-Echevarria, R., Rivera-Valdés, J. J., Rodríguez-Navarro, F. M., Rivera-Leon, E. A., & Martinez-Lopez, E. (2021). High dietary ω-6:ω-3 PUFA ratio and simple carbohydrates as a potential risk factors for gallstone disease: A cross-sectional study. Clinics and research in hepatology and gastroenterology, 101802. https://doi.org/10.1016/j.clinre.2021.101802
Campos-Perez, Wendy, et al. "High dietary ω-6:ω-3 PUFA ratio and simple carbohydrates as a potential risk factors for gallstone disease: A cross-sectional study." Clinics and research in hepatology and gastroenterology vol. (2021): 101802. doi: https://doi.org/10.1016/j.clinre.2021.101802
Campos-Perez W, Perez-Robles M, Rodriguez-Echevarria R, Rivera-Valdés JJ, Rodríguez-Navarro FM, Rivera-Leon EA, Martinez-Lopez E. High dietary ω-6:ω-3 PUFA ratio and simple carbohydrates as a potential risk factors for gallstone disease: A cross-sectional study. Clin Res Hepatol Gastroenterol. 2021 Dec 09;101802. doi: 10.1016/j.clinre.2021.101802. Epub 2021 Dec 09. PMID: 34896648.
Copy Download .nbib Format: NLM
Share it on

Clin Res Hepatol Gastroenterol. 2021 Dec 09;101802. doi: 10.1016/j.clinre.2021.101802. Epub 2021 Dec 09.

High dietary ω-6:ω-3 PUFA ratio and simple carbohydrates as a potential risk factors for gallstone disease: A cross-sectional study.

Clinics and research in hepatology and gastroenterology

Wendy Campos-Perez, Mariana Perez-Robles, Roberto Rodriguez-Echevarria, Juan J Rivera-Valdés, Fernando M Rodríguez-Navarro, Edgar A Rivera-Leon, Erika Martinez-Lopez

Affiliations

  1. Instituto de Nutrigenética y Nutrigenómica Traslacional, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México, Sierra Mojada 950, Guadalajara, Jalisco, Mexico.
  2. División de Cirugía del Hospital Civil de Guadalajara "Dr. Juan I. Menchaca", Salvador Quevedo y Zubieta 750, Guadalajara, Jalisco, Mexico.
  3. Instituto de Nutrigenética y Nutrigenómica Traslacional, Departamento de Biología Molecular y Genómica, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, México, Sierra Mojada 950, Guadalajara, Jalisco, Mexico. Electronic address: [email protected].

PMID: 34896648 DOI: 10.1016/j.clinre.2021.101802

Abstract

BACKGROUND & AIMS: Gallstone disease (GD) is a major cause for consultation at general surgery services worldwide. In fact, GD has a strong relationship with environmental factors. However, specific characteristics in the Mexican population have not been established. The aim of this study was to compare the dietary components, physical activity, body composition and serum lipids in women with and without GD.

METHODS: 54 women with GD and 75 without GD from West Mexico were enrolled in a cross-sectional study. Dietary intake was obtained through a habitual day food record and analyzed using the Nutritionist Pro

RESULTS: Women with GD presented a higher BF% (40 ± 8.7 vs 35.21 ± 9.8%, p= 0.004), an elevated dietary ω-6:ω-3 polyunsaturated fatty acids (PUFA) ratio (18.0 ± 11.4 vs 10.9 ± 4.7, p<0.001) and a higher simple carbohydrates (sCH) intake (28.3 ± 17.8 vs 13.23 ± 8.2%, p<0.001) as well as lower HDL-cholesterol levels (37.43 ± 8.5 vs 46.6 ± 12.02 mg/dL, p<0.001) compared with women without GD. Furthermore, it was foun d a higher ω-6:ω-3 PUFA ratio (OR: 3.9, 95% CI 1.52-10.38, p=0.005) and excessive sCH consumption (OR: 7.4, 95% CI 1.92-28.65, p=0.004).

CONCLUSION: We suggest that a high dietary ω-6:ω-3 PUFA ratio and an excessive sCH intake are associated with an increased risk of GD in women.

Copyright © 2021. Published by Elsevier Masson SAS.

Keywords: Gallstone disease; diet; physical activity; simple carbohydrates; ω-6:ω-3 PUFAs ratio

Conflict of interest statement

Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The

Publication Types