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J Silla KE, S Brigham K, Goldstein M, et al. Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa. Int J Eat Disord. 2021;54(12):2213-2217doi: 10.1002/eat.23622.
J Silla, K. E., S Brigham, K., Goldstein, M., Misra, M., & Singhal, V. (2021). Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa. The International journal of eating disorders, 54(12), 2213-2217. https://doi.org/10.1002/eat.23622
J Silla, Karol Elisha, et al. "Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa." The International journal of eating disorders vol. 54,12 (2021): 2213-2217. doi: https://doi.org/10.1002/eat.23622
J Silla KE, S Brigham K, Goldstein M, Misra M, Singhal V. Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa. Int J Eat Disord. 2021 Dec;54(12):2213-2217. doi: 10.1002/eat.23622. Epub 2021 Oct 07. PMID: 34617624.
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Int J Eat Disord. 2021 Dec;54(12):2213-2217. doi: 10.1002/eat.23622. Epub 2021 Oct 07.

Clinical, biochemical, and hematological characteristics of community-dwelling adolescent and young adult males with anorexia nervosa.

The International journal of eating disorders

Karol Elisha J Silla, Kathryn S Brigham, Mark Goldstein, Madhusmita Misra, Vibha Singhal

Affiliations

  1. Division of Medical Education, Weill Cornell Medicine-Qatar, Doha, Qatar.
  2. Division of Adolescent and Young Adult Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  3. Neuroendocrine Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
  4. Division of Pediatric Endocrinology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

PMID: 34617624 DOI: 10.1002/eat.23622

Abstract

OBJECTIVE: Data regarding clinical characteristics in males with AN are limited. We aimed to delineate clinical, biochemical, and hematological features in community-dwelling adolescent and young adult males with AN.

METHOD: A retrospective chart review of electronic medical records from 2000 to 2016 was conducted for 53 males aged 10-23 years old; AN (n = 36) and healthy controls (n = 17) were similar for Tanner stage.

RESULTS: Adolescent and young adult males with AN were diagnosed at a mean age of 15.9 ± 3.0 years. The most prevalent strategy for weight loss (following calorie restriction) was over-exercising. Labs demonstrated polycythemia, leukopenia, and thrombocytopenia, but no electrolyte abnormalities. Compared with healthy controls of similar Tanner stage, males with AN had lower total testosterone levels. A significant proportion of males with AN had traumatic bone fractures.

DISCUSSION: Over-exercising is a common secondary weight loss strategy in males with AN. Testosterone levels are lower than in controls, but electrolyte abnormalities are rare. With enhanced provider awareness, diagnostic delays may be prevented.

© 2021 The Authors. International Journal of Eating Disorders published by Wiley Periodicals LLC.

Keywords: adolescent health; anorexia nervosa; clinical features; eating disorders; male; physical activity; psychiatry; testosterone

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