Phys Eng Sci Med. 2021 Dec;44(4):1331-1340. doi: 10.1007/s13246-021-01066-3. Epub 2021 Oct 25.
Physical and engineering sciences in medicine
Sijan Gautam
PMID: 34694586 DOI: 10.1007/s13246-021-01066-3
Glomerular filtration rate (GFR) varies with age, the calculation method, and the correction factor for slope-intercept overestimation. Hence, any normal reference range accompanying the results should be suitably adapted to the method used. For Nuclear Medicine Departments using a two-sample slope-intercept method, the lack of appropriate age-specific normal reference range has been a hindrance to adopting the recently updated Jodal Brochner-Mortensen (JBM) correction over other older and more widely used methods. A retrospective analysis of the routine GFR calculation and clinical reports generated locally from 2006 to 2020 was carried out. GFR was calculated with
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Keywords: Age-specific GFR normal reference range; Chromium 51Cr-EDTA; Glomerular Filtration Rate (GFR); Jodal Brochner-Mortensen method; Technetium 99mTc-DTPA