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Head Neck Pathol. 2021 Dec;15(4):1328-1334. doi: 10.1007/s12105-020-01275-4. Epub 2021 Jan 04.

Epithelioid Sarcoma of the External Auditory Canal: An Uncommon Tumor at an Unusual Site and a Brief Overview of the Literature.

Head and neck pathology

Bingcheng Wu, Joshua Kai Xun Tay, Woei Shyang Loh, Fredrik Petersson

Affiliations

  1. Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
  2. Department of Otolaryngology, National University Health System, Singapore, Singapore.
  3. Department of Pathology, National University Health System, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore. [email protected].

PMID: 33394376 PMCID: PMC8633210 DOI: 10.1007/s12105-020-01275-4

Abstract

We present a case (41 years old pregnant female) with epithelioid sarcoma arising in the left external auditory canal. On immunohistochemistry, the tumor cell diffusely expressed cytokeratins and showed patchy expression of ERG and CD34. The neoplastic cells demonstrated uniform loss of INI1-expression. Epithelioid sarcoma arising in the external auditory canal is rare. Awareness that ES may rarely arise at unusual sites is of critical importance in order to apply a broad enough panel in the immunohistochemical study, so a misdiagnosis of carcinoma can be avoided.

© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC part of Springer Nature.

Keywords: Ear; Epithelioid sarcoma; External auditory canal; Head and neck

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