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Stabouli S, Polderman N, Nelms CL, et al. Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatr Nephrol. 2021;37(1):1-20doi: 10.1007/s00467-021-05148-y.
Stabouli, S., Polderman, N., Nelms, C. L., Paglialonga, F., Oosterveld, M. J. S., Greenbaum, L. A., Warady, B. A., Anderson, C., Haffner, D., Desloovere, A., Qizalbash, L., Renken-Terhaerdt, J., Tuokkola, J., Walle, J. V., Shaw, V., Mitsnefes, M., & Shroff, R. (2022). Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatric nephrology (Berlin, Germany), 37(1), 1-20. https://doi.org/10.1007/s00467-021-05148-y
Stabouli, Stella, et al. "Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce." Pediatric nephrology (Berlin, Germany) vol. 37,1 (2022): 1-20. doi: https://doi.org/10.1007/s00467-021-05148-y
Stabouli S, Polderman N, Nelms CL, Paglialonga F, Oosterveld MJS, Greenbaum LA, Warady BA, Anderson C, Haffner D, Desloovere A, Qizalbash L, Renken-Terhaerdt J, Tuokkola J, Walle JV, Shaw V, Mitsnefes M, Shroff R. Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce. Pediatr Nephrol. 2022 Jan;37(1):1-20. doi: 10.1007/s00467-021-05148-y. Epub 2021 Aug 10. PMID: 34374836.
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Pediatr Nephrol. 2022 Jan;37(1):1-20. doi: 10.1007/s00467-021-05148-y. Epub 2021 Aug 10.

Assessment and management of obesity and metabolic syndrome in children with CKD stages 2-5 on dialysis and after kidney transplantation-clinical practice recommendations from the Pediatric Renal Nutrition Taskforce.

Pediatric nephrology (Berlin, Germany)

Stella Stabouli, Nonnie Polderman, Christina L Nelms, Fabio Paglialonga, Michiel J S Oosterveld, Larry A Greenbaum, Bradley A Warady, Caroline Anderson, Dieter Haffner, An Desloovere, Leila Qizalbash, José Renken-Terhaerdt, Jetta Tuokkola, Johan Vande Walle, Vanessa Shaw, Mark Mitsnefes, Rukshana Shroff

Affiliations

  1. 1st Department of Pediatrics, Hippokration Hospital, Aristotle University Thessaloniki, 49 Konstantinoupoleos Str, 54642, Thessaloniki, Greece. [email protected].
  2. British Columbia Children's Hospital, Vancouver, Canada.
  3. University of Nebraska, Kearney, NE, USA.
  4. Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
  5. Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands.
  6. Emory University, Atlanta, GA, USA.
  7. Children's Healthcare of Atlanta, Atlanta, GA, USA.
  8. Children's Mercy Kansas City, Kansas City, MO, USA.
  9. University Hospital Southampton NHS Foundation Trust, Southampton, UK.
  10. Children's Hospital, Hannover Medical School, Hannover, Germany.
  11. University Hospital Ghent, Ghent, Belgium.
  12. Great Northern Children's Hospital, Newcastle upon Tyne, UK.
  13. Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.
  14. Children's Hospital and Clinical Nutrition Unit, Internal Medicine and Rehabilitation, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  15. University College London Great Ormond Street Hospital Institute of Child Health, London, UK.
  16. Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

PMID: 34374836 DOI: 10.1007/s00467-021-05148-y

Abstract

Obesity and metabolic syndrome (O&MS) due to the worldwide obesity epidemic affects children at all stages of chronic kidney disease (CKD) including dialysis and after kidney transplantation. The presence of O&MS in the pediatric CKD population may augment the already increased cardiovascular risk and contribute to the loss of kidney function. The Pediatric Renal Nutrition Taskforce (PRNT) is an international team of pediatric renal dietitians and pediatric nephrologists who develop clinical practice recommendations (CPRs) for the nutritional management of children with kidney diseases. We present CPRs for the assessment and management of O&MS in children with CKD stages 2-5, on dialysis and after kidney transplantation. We address the risk factors and diagnostic criteria for O&MS and discuss their management focusing on non-pharmacological treatment management, including diet, physical activity, and behavior modification in the context of age and CKD stage. The statements have been graded using the American Academy of Pediatrics grading matrix. Statements with a low grade or those that are opinion-based must be carefully considered and adapted to individual patient needs based on the clinical judgment of the treating physician and dietitian. Research recommendations are provided. The CPRs will be periodically audited and updated by the PRNT.

© 2021. The Author(s).

Keywords: Chronic kidney disease; Clinical practice recommendations; Diet; Kidney transplantation; Metabolic syndrome; Obesity; Pediatric Renal Nutrition Taskforce; Physical activity; Screen time; Sleep

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