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Iran J Microbiol. 2021 Oct;13(5):691-702. doi: 10.18502/ijm.v13i5.7436.

Biological characteristics and anti-biofilm activity of a lytic phage against vancomycin-resistant .

Iranian journal of microbiology

Forough Goodarzi, Masoumeh Hallajzadeh, Mohammad Sholeh, Malihe Talebi, Vahid Pirhajati Mahabadi, Nour Amirmozafari

Affiliations

  1. Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  2. Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran.
  3. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.

PMID: 34900167 PMCID: PMC8629820 DOI: 10.18502/ijm.v13i5.7436

Abstract

BACKGROUND AND OBJECTIVES: An important leading cause of the emergence of vancomycin-resistant enterococci, especially

MATERIALS AND METHODS: A highly effective bacteriophage against vancomycin-resistant

RESULTS: Phage S2 was specifically capable of lysing a wide range of clinical

CONCLUSION: According to the results, phage S2 could potentially be an alternative for the elimination and control of vancomycin-resistant

Copyright © 2021 The Authors. Published by Tehran University of Medical Sciences.

Keywords: Antibiotic-resistance; Biofilm; Enterococcus faecium; Phage therapy; Vancomycin-resistant Enterococcus faecium

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