Display options
Cite
Jain RK, Choudhary GM, Gupta G, et al. Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma. Asian J Transfus Sci. 2021;15(2):195-198doi: 10.4103/ajts.AJTS_39_17.
Jain, R. K., Choudhary, G. M., Gupta, G., Patil, A. N., Prakash, G. D., & Jain, A. K. (2021). Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma. Asian journal of transfusion science, 15(2), 195-198. https://doi.org/10.4103/ajts.AJTS_39_17
Jain, Rakesh Kumar, et al. "Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma." Asian journal of transfusion science vol. 15,2 (2021): 195-198. doi: https://doi.org/10.4103/ajts.AJTS_39_17
Jain RK, Choudhary GM, Gupta G, Patil AN, Prakash GD, Jain AK. Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma. Asian J Transfus Sci. 2021 Jul-Dec;15(2):195-198. doi: 10.4103/ajts.AJTS_39_17. Epub 2021 Nov 01. PMID: 34908754; PMCID: PMC8628236.
Copy Download .nbib Format: NLM
Share it on

Asian J Transfus Sci. 2021 Jul-Dec;15(2):195-198. doi: 10.4103/ajts.AJTS_39_17. Epub 2021 Nov 01.

Reducing split-thickness skin grafting donor site agony; faster healing and decreased pain-role of platelet-rich plasma.

Asian journal of transfusion science

Rakesh Kumar Jain, Ghisulal M Choudhary, Gajendra Gupta, Aditya N Patil, Gautam D Prakash, Ayush K Jain

Affiliations

  1. Department of Plastic Surgery, SMS Hospital and Medical College, Jaipur, Rajasthan, India.
  2. Department of Pathology, Santokba Durlabji Hospital, Jaipur, Rajasthan, India.

PMID: 34908754 PMCID: PMC8628236 DOI: 10.4103/ajts.AJTS_39_17

Abstract

INTRODUCTION: The split-thickness skin graft harvested donor site is associated with prolonged healing, discomfort, and pain. Platelet-rich plasma (PRP) contains platelet-derived growth factors and has been widely used in chronic wounds and skin graft donor sites. PRP application is known to accelerate wound epithelialization rates, and also reduce postoperative wound site pain.

MATERIALS AND METHODS: We assessed 20 patients admitted to our hospital service who underwent split-thickness skin grafting (STSGs) with proximal half of the donor site treated with PRP. The dressing was conducted on postoperative day 7, 14, and 21. The donor site healing was assessed with serial photographs and donor site pain measured by numerical rating scale.

RESULTS: Complete healing of wounds (epithelialization) was present in 12 (60%) patients dressed with PRP. Pain on opening dressing was an average of 3.5 in PRP dressed wounds and 6.35 in control wounds. Patients dressed without PRP, none of them had complete epithelialization. All patients had partial healing and were less than the donor site dressed with PRP. Based on these results, skin graft donor site with PRP showed accelerated healing and reduced pain and discomfort compared to control without PRP.

CONCLUSION: PRP is a beneficial adjunct for reducing donor site pain and increased healing of donor site following STSG harvest.

Copyright: © 2021 Asian Journal of Transfusion Science.

Keywords: Platelet-rich plasma; skin graft donor site dressing; skin grafting

Conflict of interest statement

There are no conflicts of interest.

References

  1. Injury. 2009 Aug;40(8):801-5 - PubMed
  2. Ann Plast Surg. 1991 Sep;27(3):288-91 - PubMed
  3. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Jun;85(6):638-46 - PubMed
  4. J Oral Implantol. 2013 Oct;39(5):525-32 - PubMed
  5. Eur Spine J. 2003 Aug;12(4):400-7 - PubMed
  6. J Burn Care Rehabil. 1987 Sep-Oct;8(5):384-6 - PubMed
  7. Med Mol Morphol. 2011 Dec;44(4):233-6 - PubMed
  8. J Clin Nurs. 2005 Aug;14(7):798-804 - PubMed
  9. J Artif Organs. 2014 Jun;17(2):186-92 - PubMed
  10. Int J Nurs Pract. 2003 Apr;9(2):S9-17 - PubMed
  11. Diabetes Care. 2001 Mar;24(3):483-8 - PubMed
  12. Semin Cutan Med Surg. 2003 Dec;22(4):295-305 - PubMed
  13. Plast Reconstr Surg. 2008 Nov;122(5):1352-1360 - PubMed
  14. Diabet Foot Ankle. 2015 Jan 22;6:24972 - PubMed
  15. Plast Reconstr Surg. 2008 Nov;122(5):1431-1440 - PubMed
  16. Plast Reconstr Surg. 2001 Jan;107(1):229-37; discussion 238-9 - PubMed
  17. Appl Nurs Res. 1998 Nov;11(4):174-82 - PubMed
  18. Science. 1997 Apr 4;276(5309):75-81 - PubMed

Publication Types