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Wing SE, Hu H, Lopez L, et al. Recall of Genomic Testing Results Among Patients with Cancer. Oncologist. 2021;26(12):e2302-e2305doi: 10.1002/onco.13928.
Wing, S. E., Hu, H., Lopez, L., Solomon, I., Shen, J., Raquel, C., Sur, M., Chao, J., Cristea, M., Fakih, M., Mortimer, J., Pal, S., Reckamp, K., Yuan, Y., & Gray, S. W. (2021). Recall of Genomic Testing Results Among Patients with Cancer. The oncologist, 26(12), e2302-e2305. https://doi.org/10.1002/onco.13928
Wing, Sam E, et al. "Recall of Genomic Testing Results Among Patients with Cancer." The oncologist vol. 26,12 (2021): e2302-e2305. doi: https://doi.org/10.1002/onco.13928
Wing SE, Hu H, Lopez L, Solomon I, Shen J, Raquel C, Sur M, Chao J, Cristea M, Fakih M, Mortimer J, Pal S, Reckamp K, Yuan Y, Gray SW. Recall of Genomic Testing Results Among Patients with Cancer. Oncologist. 2021 Dec;26(12):e2302-e2305. doi: 10.1002/onco.13928. Epub 2021 Aug 26. PMID: 34355454.
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Oncologist. 2021 Dec;26(12):e2302-e2305. doi: 10.1002/onco.13928. Epub 2021 Aug 26.

Recall of Genomic Testing Results Among Patients with Cancer.

The oncologist

Sam E Wing, Hengrui Hu, Lisa Lopez, Ilana Solomon, Jenny Shen, Catherine Raquel, Melissa Sur, Joseph Chao, Mihaela Cristea, Marwan Fakih, Joanne Mortimer, Sumanta Pal, Karen Reckamp, Yuan Yuan, Stacy W Gray

Affiliations

  1. Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
  2. Department of Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  3. School of Nursing, University of Texas at Austin, Austin, Texas, USA.
  4. Department of Medical Oncology & Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA.
  5. Department of Psychology, Stony Brook University, Stony Brook, New York, USA.
  6. College of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.
  7. University of South Florida, Morsani College of Medicine, Tampa, Florida, USA.
  8. Department of Medical Oncology, Cedars-Sinai Medical Center, California, Los Angeles, USA.

PMID: 34355454 DOI: 10.1002/onco.13928

Abstract

BACKGROUND: Genomic testing of somatic and germline DNA has transformed cancer care. However, low genetic knowledge among patients may compromise care and health outcomes. Given the rise in genomic testing, we sought to understand patients' knowledge of their genetic test results.

MATERIALS AND METHODS: We conducted a survey-based study with 85 patients at a comprehensive cancer center. We compared self-reported recall of (a) having had somatic/germline testing and (b) their specific somatic/germline results to the genomic test results documented in the medical record.

RESULTS: Approximately 30% of patients did not recall having had testing. Of those who recalled having testing, 44% of patients with pathogenic/likely pathogenic germline mutations and 57% of patients with reported somatic alterations did not accurately recall their specific gene or variant-level results.

CONCLUSION: Given significant knowledge gaps in patients' recall of genomic testing, there is a critical need to improve patient-directed education and return-of-results strategies.

© 2021 The Authors. The Oncologist published by Wiley Periodicals LLC on behalf of AlphaMed Press.

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