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Clin Imaging. 2021 Nov 03;82:15-20. doi: 10.1016/j.clinimag.2021.10.011. Epub 2021 Nov 03.

Feasibility of sub-second CT angiography of the abdomen and pelvis with very low volume of contrast media, low tube voltage, and high-pitch technique, on a third-generation dual-source CT scanner.

Clinical imaging

Faezeh Sodagari, Cecil G Wood, Rishi Agrawal, Vahid Yaghmai

Affiliations

  1. Department of Radiology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA. Electronic address: [email protected].
  2. Department of Radiology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA. Electronic address: [email protected].
  3. Department of Radiology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA. Electronic address: [email protected].
  4. Department of Radiology, Northwestern University-Feinberg School of Medicine, Chicago, IL, USA; Department of Radiological Sciences, University of California, Irvine School of Medicine, Orange, CA, USA. Electronic address: [email protected].

PMID: 34768221 DOI: 10.1016/j.clinimag.2021.10.011

Abstract

BACKGROUND: Concerns about potential risks of using contrast media in patients with chronic renal insufficiency limit the utilization of CT angiography in this population.

PURPOSE: To evaluate the feasibility of abdominopelvic CTA with very low volumes of contrast media.

MATERIAL AND METHODS: In this retrospective study, 20 patients with chronic renal insufficiency underwent high-pitch abdominopelvic (AP) CTA on a third-generation dual-source CT scanner with 30 mL of nonionic iodinated contrast. The homogeneity of intravascular attenuation at the suprarenal aorta, infrarenal aorta, and the right common iliac artery was measured. Image noise, contrast-to-noise ratio (CNR), and signal-to-noise ratio (SNR) were used to assess objective image quality. Subjective image quality was evaluated on a 5-point scale (1 = unacceptable; 5 = excellent).

RESULTS: Twelve male and eight female patients underwent CTA of the abdomen and pelvis at 80 kVp. Five CTAs also included the chest (CAP). The mean scan duration was 0.78 ± 0.19 s for AP and 0.96 ± 0.06 s for CAP CTAs. The mean ± SD of attenuation at suprarenal aorta, infrarenal aorta, and right common iliac artery were 235.1 ± 68.0, 249.2 ± 61.3, and 254.4 ± 67.7 HU, respectively. The attenuation was homogeneous across vascular levels (P = 0.06). All scans had diagnostic subjective image quality with the median (IQR) of 3.5 (1.75). CNR and SNR were homogeneous across vascular levels (P = 0.08 and P = 0.14, respectively).

CONCLUSION: Sub-second, high-pitch abdominopelvic CTA with a low volume of contrast in patients with chronic renal insufficiency is technically and clinically feasible with good diagnostic image quality and homogenous attenuation across vascular levels.

Copyright © 2021 Elsevier Inc. All rights reserved.

Keywords: CT angiography; Contrast medium; Dual-source CT; Intravascular attenuation; Low kVp

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