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Hu Y, Lei D, Wu D, et al. Residual β-lactam antibiotics and ecotoxicity to Vibrio fischeri, Daphnia magna of pharmaceutical wastewater in the treatment process. J Hazard Mater. 2021;425:127840doi: 10.1016/j.jhazmat.2021.127840.
Hu, Y., Lei, D., Wu, D., Xia, J., Zhou, W., & Cui, C. (2021). Residual β-lactam antibiotics and ecotoxicity to Vibrio fischeri, Daphnia magna of pharmaceutical wastewater in the treatment process. Journal of hazardous materials, 425127840. https://doi.org/10.1016/j.jhazmat.2021.127840
Hu, Yaru, et al. "Residual β-lactam antibiotics and ecotoxicity to Vibrio fischeri, Daphnia magna of pharmaceutical wastewater in the treatment process." Journal of hazardous materials vol. 425 (2021): 127840. doi: https://doi.org/10.1016/j.jhazmat.2021.127840
Hu Y, Lei D, Wu D, Xia J, Zhou W, Cui C. Residual β-lactam antibiotics and ecotoxicity to Vibrio fischeri, Daphnia magna of pharmaceutical wastewater in the treatment process. J Hazard Mater. 2021 Nov 22;425:127840. doi: 10.1016/j.jhazmat.2021.127840. Epub 2021 Nov 22. PMID: 34896711.
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J Hazard Mater. 2021 Nov 22;425:127840. doi: 10.1016/j.jhazmat.2021.127840. Epub 2021 Nov 22.

Residual β-lactam antibiotics and ecotoxicity to Vibrio fischeri, Daphnia magna of pharmaceutical wastewater in the treatment process.

Journal of hazardous materials

Yaru Hu, Dandan Lei, Da Wu, Jing Xia, Wang Zhou, Changzheng Cui

Affiliations

  1. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China. Electronic address: [email protected].
  2. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China.
  3. North China Pharmaceutical Huangsheng Co. Ltd, Shijiangzhuang, Hebei 052160, China.
  4. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, School of Resources and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China; Shanghai Environmental Protection Key Laboratory on Environmental Standard and Risk Management of Chemical Pollutants, East China University of Science & Technology, Shanghai 200237, China.

PMID: 34896711 DOI: 10.1016/j.jhazmat.2021.127840

Abstract

The discharge of pharmaceutical wastewater introduces numerous pollutants into the environment, and their pollution level reduction has aroused extensive concern. This study investigated the variation in residual antibiotics and ecotoxicity to two nutritional-level model organisms in the pharmaceutical wastewater treatment process (PWTP). The wastewater in the equalization tank contained massive organic matters (2.9-18.7 times higher than the permissible values in GB21903-2008) and antibiotics (310.88 μg/L), posing extremely toxic effects to Vibrio fischeri (V. fischeri) and Daphnia magna (D. magna). The biological anaerobic/aerobic treatment units contributed the most to the reduction of antibiotics and the ecotoxicity to both organisms, with the removal rates of 72% and > 90%, respectively. The ecotoxicity of pharmaceutical wastewater was strongly and positively correlated with the residual antibiotics, amoxicillin, cephalexin, ammonia nitrogen, and total phosphorus (P < 0.05). However, the detected amounts of amoxicillin and cephalexin were approximately 10

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Keywords: Anaerobic/aerobic treatment; Antibiotics; Ecotoxicity; Pharmaceutical wastewater treatment process; Toxic unit (TU(50))

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