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Clin Endosc. 2021 Nov;54(6):825-832. doi: 10.5946/ce.2021.048. Epub 2021 May 27.

Endoscopic Evaluation of Biliary Strictures: Current and Emerging Techniques.

Clinical endoscopy

Roy Huynh, Corinne Owers, Christopher Pinto, Thuy-My Nguyen, Titus Kwok

Affiliations

  1. Department of Upper Gastrointestinal Surgery, Concord Repatriation General Hospital, Sydney, NSW, Australia.
  2. Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.

PMID: 34038998 PMCID: PMC8652159 DOI: 10.5946/ce.2021.048

Abstract

The diagnosis of biliary strictures in clinical practice can be challenging. Discriminating between benign and malignant biliary strictures is important to prevent the morbidity and mortality associated with incorrect diagnoses. Missing a malignant biliary stricture may delay surgery, resulting in poor prognostic outcomes. Conversely, it has been demonstrated that approximately 20% of patients who undergo surgery for suspected biliary malignancies have a benign etiology on histopathology. Traditional tissue sampling using endoscopic retrograde cholangiography does not always produce a definitive diagnosis, with a considerable proportion of cases remaining as indeterminate biliary strictures. Recent advances in endoscopic techniques have the potential to improve the diagnostic and prognostic accuracy of biliary strictures.

Keywords: Bile ducts; Biliary tract neoplasm; Cholestasis; Endoscopy; Pathologic constriction

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