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Clin Case Rep. 2021 Dec 09;9(12):e05157. doi: 10.1002/ccr3.5157. eCollection 2021 Dec.

Reversible blindness after erroneous prescription of closantel: A case report.

Clinical case reports

Hamed Cheraghmakani, Reza Jafari, Elahe Karimpour-Razkenari, Monireh Ghazaeian

Affiliations

  1. Department of Neurology Faculty of Medicine Mazandaran University of Medical Sciences Sari Iran.
  2. Department of Ophthalmology Faculty of Medicine Mazandaran University of Medical Sciences Sari Iran.
  3. Department of Clinical Pharmacy Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.
  4. Pharmaceutical Sciences Research Center Department of Clinical Pharmacy Faculty of Pharmacy Mazandaran University of Medical Sciences Sari Iran.

PMID: 34938546 PMCID: PMC8659543 DOI: 10.1002/ccr3.5157

Abstract

A 20-year-old girl was referred with vision loss upon closantel use. Plasma exchange and high-dose corticosteroid pulse therapy were administered. A 2.5-year follow-up showed improved vision and increased layer thickness of the peripheral nerve fiber. Early treatment with plasma exchange and high-dose corticosteroid therapy can be beneficial to reverse closantel toxicity.

© 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Keywords: blindness; closantel; toxicity

Conflict of interest statement

The authors declare that they have no competing interests.

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