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J Clin Transl Endocrinol Case Rep. 2022 Mar;23:100104. doi: 10.1016/j.jecr.2021.100104. Epub 2021 Dec 17.

A case report of new onset graves' disease induced by SARS-CoV-2 infection or vaccine?.

Journal of clinical and translational endocrinology case reports

Walid Hamouche, Yahya El Soufi, Saleh Alzaraq, Belonwu Valentine Okafor, Fan Zhang, Christos Paras

Affiliations

  1. Internal Medicine Department, Brookdale University Hospital Medical Center, 1 Brookdale Plaza, Brooklyn, NY, USA.
  2. Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
  3. Faculty of Medicine, Jordan University of Science and Technology, Amman, Jordan.
  4. Nnmadi Azikiwe University Teaching Hospital, Nnewi, Nigeria.
  5. Division of Endocrinology, Diabetes & Metabolism, Brookdale University Hospital Medical Center, 1 Brookdale Plaza, Brooklyn, NY, USA.
  6. Division of Endocrinology, Diabetes & Metabolism, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, USA.

PMID: 34934633 PMCID: PMC8679515 DOI: 10.1016/j.jecr.2021.100104

Abstract

The virus responsible for the COVID-19 pandemic continues to pose unmatched challenges in the world. It can cause systemic inflammation, which can lead to multiorgan involvement and subsequent damage. The relationship that possibly exists between the COVID-19 infection, the newly developed vaccines, and thyroid disease are still under extensive investigation. We are reporting the first case of new-onset graves' disease in a young, healthy man after COVID-19 infection and receiving a COVID-19 vaccine dose.

© 2021 The Authors.

Keywords: COVID-19; Graves' disease; Hyperthyroidism; Vaccine

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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